China Factory Direct
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| CAS number | 52215-41-5 |
| Product name | 3-Fluoro-5-methylaniline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of active pharmaceutical ingredients (APIs), including antidepressants and antipsychotics | Used to construct aromatic amine structural units via nucleophilic substitution, diazotization, or coupling reactions |
| Pesticides | Key intermediate for synthesizing agrochemicals such as herbicides and insecticides | Undergoes electrophilic aromatic substitution to introduce fluorine and methyl functional groups, optimizing biological activity |
| Dyes & Pigments | Precursor for high-performance organic pigments and functional dyes | Subjected to diazotization followed by coupling to produce azo colorants |
| Materials Science | Functional monomer for synthesizing liquid crystal monomers or polymeric materials | Incorporated into polymer backbones or side chains via amidation, etherification, and related reactions |
| Test Item | Common Testing Method | Method Overview |
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| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Uses a reverse-phase C18 column with methanol/water or acetonitrile/water as the mobile phase. A UV-VIS detector is used at 254 nm or 260 nm for detection. This method effectively separates the target compound from impurities, providing accurate quantification and is suitable for purity determination of active pharmaceutical ingredients and intermediates. |
| Content Determination | Gas Chromatography (GC) | Suitable for analysis of volatile components. Utilizes capillary columns (e.g., DB-5 or HP-5) with nitrogen or helium as carrier gas and FID or MS as detectors. Sample derivatization (e.g., acetylation) is required to enhance volatility and stability. |
| Impurity Analysis | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines the separation capability of HPLC with the qualitative and quantitative advantages of mass spectrometry. It can identify structural analogs, synthetic byproducts, and degradation products. Suitable for trace impurity identification and quantification, meeting ICH Q3A/B requirements. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide detailed molecular structure information, confirming substitution positions, functional groups, and isomerism in 3-fluoro-5-methyl aniline. It is considered the gold standard for structural confirmation. |
| Organic Impurity Screening | Gas Chromatography-Mass Spectrometry (GC-MS) | Used to detect residual solvents and volatile organic impurities. Selective ion monitoring (SIM) mode improves sensitivity, commonly applied in process optimization and safety assessment. |
| Water Content | Karl Fischer Titration | Suitable for determining trace amounts of water in samples. Coulometric or volumetric methods are selected based on sample properties. Accurate results make it widely used in quality control of solid raw materials. |
| Melting Point Determination | Micro Melting Point Apparatus Method | Determines the melting point by observing temperature changes during the melting process, indicating purity and crystalline state. The typical melting point of 3-fluoro-5-methyl aniline is approximately 75–78 °C; deviations may indicate impurities. |
| UV-Visible Spectral Analysis (UV-Vis) | UV-Vis Spectrophotometry | Exhibits characteristic absorption peaks between 254–270 nm, useful for rapid qualitative screening and auxiliary quantitative analysis. However, it cannot distinguish structurally similar impurities. |
| Test Item | Specification |
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| Appearance | Brown liquid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
| Refractive Index (n20/D) | 1.540–1.545 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.