China Factory Direct
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| CAS number | 52415-29-9 |
| Product name | 6-Bromo-1H-indole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate synthesis | Used as an intermediate for constructing indole-containing drug molecules, applied in the synthesis of bioactive compounds such as antitumor and anti-inflammatory agents |
| Organic synthesis | Preparation of halogenated aryl derivatives | Functional group introduction via transition metal-catalyzed reactions, including Suzuki coupling and Heck reaction |
| Agrochemical R&D | Insecticide/fungicide intermediate | Applied in the synthesis of biologically active heterocyclic agrochemical compounds |
| Materials science | Functional material precursor | Used to prepare organic semiconductor materials with optoelectronic properties or fluorescent probes |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 6-bromoindole by separation on a reversed-phase column and UV detection at ~280 nm, comparing peak area to a calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., brominated isomers, indole, debrominated products) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., DMF, dichloromethane, methanol) by gas chromatographic separation with flame ionization detection. |
| Moisture Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration where iodine reacts stoichiometrically with water in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-OES | Measures total elemental metal impurities (e.g., Pb, Cd, Hg, Ni) after acid digestion by atomic emission spectroscopy at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using an anion-exchange column and suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines the temperature range over which the solid transitions to liquid, indicating purity and identity based on crystalline homogeneity. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles or discoloration under controlled white light against a white background. |
| Loss on Drying | Gravimetric Analysis | Measures mass loss after drying under specified temperature/vacuum conditions, reflecting volatile content including residual solvents and moisture. |
| Residue on Ignition | Sulfated Ash Test | Quantifies inorganic residue remaining after high-temperature incineration, indicating non-volatile inorganic impurities. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral purity (though 6-bromoindole is achiral, detects potential chiral contaminants). |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of a defined suspension in water, indicating acidic/basic impurities or degradation products. |
| Test Item | Specification |
|---|---|
| Appearance | Orange solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 112–116°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.