4-Bromoindole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 52488-36-5 |
| Product name | 4-Bromoindole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromoindole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromoindole Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromoindole
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate for synthesizing antitumor agents (e.g., Sunitinib analogs) | Applied in palladium-catalyzed cross-coupling reactions (Suzuki, Heck) |
| Agrochemical R&D | Structural modification unit for novel insecticidal molecules | Applied in electrophilic substitution or metal-catalyzed C–H bond functionalization |
| Materials Science | Precursor for organic optoelectronic materials (e.g., OLED hole-transport layers) | Multi-step organic synthesis, including N-protection, bromination, coupling, and deprotection |
| Chemical Reagents | Standard brominated derivative for structure–activity relationship (SAR) studies of indole derivatives | Used directly as an electrophile in cycloaddition or substitution reactions |
Manufacturing Quality Control of 4-Bromoindole
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities. Typically a white to pale yellow solid; should be dry and free of caking. |
| Content/Purity | High-Performance Liquid Chromatography (HPLC) | Utilize a reversed-phase column (e.g., C18) with a UV detector (commonly set at 254 nm or 280 nm); quantify the main component content and assess purity based on retention time and peak area. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H-NMR and ¹³C-NMR to confirm the compound structure by analyzing whether the proton and carbon spectral signals match the standard spectrum of 4-bromoindole. |
| Structure Confirmation | Mass Spectrometry (MS) | Employ EI-MS or ESI-MS to determine the molecular ion peak, confirming the molecular weight (molecular weight of 4-bromoindole is approximately 207.05 g/mol) to assist in structural identification. |
| Melting Point | Melting Point Determination (Capillary Method) | Measure the melting temperature of the sample using a melting point apparatus and compare it with the literature value (melting point of 4-bromoindole is approximately 68–72°C) to assess purity and consistency. |
| Water Content | Karl Fischer Titration | Accurately determine the water content in the sample; suitable for quality control of moisture-sensitive organic intermediates. |
| Related Substances/Impurities | High-Performance Liquid Chromatography (HPLC) | Separate potential synthetic by-products (e.g., unreacted starting materials, isomers, oxidized products) using gradient elution; calculate the peak areas of each impurity and control them within specified limits. |
| Residual Solvents | Gas Chromatography (GC) | Determine residual organic solvents potentially present from the manufacturing process (e.g., toluene, ethanol, DMF), and control them according to ICH guidelines. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detect heavy metal residues such as lead, mercury, cadmium, and arsenic to ensure compliance with pharmaceutical or high-purity reagent standards. |
| Residue on Ignition | Sulfated Ash Test | Ignite the sample at high temperature and weigh the residual ash to evaluate the level of inorganic impurities; commonly used in active pharmaceutical ingredient quality control. |
Technical Specifications of 4-Bromoindole
| Test Item | Specification |
|---|---|
| Appearance | Brown liquid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromoindole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromoindole
Packaging of 4-Bromoindole
Industrial 4-Bromoindole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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