5-Fluoro-2-iodobenzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 52548-63-7 |
| Product name | 5-Fluoro-2-iodobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Fluoro-2-iodobenzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Fluoro-2-iodobenzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Fluoro-2-iodobenzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of fluorinated drug molecules, such as antitumor or antiviral compounds | Employed as an aryl iodide in Suzuki, Heck, and other coupling reactions to construct complex molecular frameworks |
| Pesticide Development | Serves as a fluorinated aromatic building block for synthesizing novel pesticide active ingredients | Introduced into target molecules via derivatization of the carboxylic acid group or cross-coupling involving the iodine atom |
| Materials Science | Used to prepare fluorinated functional materials, such as liquid crystal or organic semiconductor precursors | Modified directionally or polymerized using both the iodine and carboxyl functional groups |
| Organic Synthesis Reagent | Functions as a multifunctional aromatic building block for constructing complex molecules | The carboxyl group can be converted to acid chlorides, esters, or amides; the iodine atom is applicable in metal-catalyzed couplings or nucleophilic substitutions |
Manufacturing Quality Control of 5-Fluoro-2-iodobenzoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., des-iodo, des-fluoro, ester, or dimeric by-products) using gradient elution and spectral or mass confirmation. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify low-boiling organic solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C guidelines. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification of trace metal impurities after acid digestion, offering sub-ppt detection limits and compliance with ICH Q3D. |
| Moisture Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Ignition of sample at 700–800 °C followed by weighing of inorganic residue to assess inorganic impurities and catalyst residues. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating; verifies identity and detects gross impurities via depression or broadening of melting range. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Quantification of chloride ions (e.g., from residual HCl or chlorinated side products) via conductivity detection or silver nitrate titration with endpoint detection. |
| Iodine Content | Oxidimetric Titration (e.g., Na₂S₂O₃ after KI liberation) | Iodide released from organic iodine under reducing conditions is titrated iodometrically to verify stoichiometric iodine incorporation. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10/D50/D90 values, ensuring consistency for downstream processing (e.g., filtration, formulation). |
Technical Specifications of 5-Fluoro-2-iodobenzoic acid
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 172–176°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Fluoro-2-iodobenzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Fluoro-2-iodobenzoic acid
Packaging of 5-Fluoro-2-iodobenzoic acid
Industrial 5-Fluoro-2-iodobenzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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