HUWENTOXIN IV Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 526224-73-7 |
| Product name | HUWENTOXIN IV |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for HUWENTOXIN IV
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk HUWENTOXIN IV Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of HUWENTOXIN IV
| Industry | Application | Process |
|---|---|---|
| Biomedical Research | Molecular probe for functional studies of ion channels (particularly Nav1.7) | Used as a high-selectivity inhibitor in in vitro electrophysiological assays (e.g., patch-clamp techniques) |
| Pharmaceutical Development | Lead compound screening and optimization for pain-targeted therapeutics | Applied in structure-based drug design (SBDD) and structure–activity relationship (SAR) studies to develop novel analgesics |
| Neuroscience | Investigation of mechanisms regulating sensory neuron excitability | Applied in ex vivo neuronal culture models, combined with calcium imaging or action potential recording for functional characterization |
Manufacturing Quality Control of HUWENTOXIN IV
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Identity Confirmation | LC-MS/MS | Uses tandem mass spectrometry coupled with liquid chromatography to verify molecular weight and sequence-specific fragmentation pattern. |
| Purity (Main Component) | RP-HPLC with UV detection | Separates components by hydrophobicity on a C18 column and quantifies peak area at 214 nm relative to total chromatographic area. |
| Related Substances | RP-HPLC with gradient elution | Detects structurally similar impurities (e.g., deletion sequences, oxidation products) using optimized mobile phase gradients and UV detection. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between iodine, sulfur dioxide, and water in anhydrous methanol/pyridine medium. |
| Residual Solvents | GC-FID | Quantifies volatile organic solvents (e.g., acetonitrile, DCM) by gas chromatographic separation followed by flame ionization detection. |
| Heavy Metals | ICP-MS | Detects trace metal contaminants (e.g., Pb, Cd, Hg) by atomization, ionization, and mass-selective detection of elemental ions. |
| Endotoxin Level | LAL Assay | Measures bacterial endotoxin using Limulus amebocyte lysate reagent that forms a gel or chromogenic complex in presence of endotoxin. |
| Peptide Content (Assay) | Amino Acid Analysis (AAA) after acid hydrolysis | Determines molar concentration by quantifying constituent amino acids via pre-column derivatization and HPLC separation. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation of plane-polarized light at 589 nm to confirm chiral integrity and stereochemical consistency. |
| pH (1% w/v solution) | Potentiometric pH measurement | Determines hydrogen ion activity in aqueous solution using calibrated glass electrode and reference electrode. |
| Bioburden | Membrane Filtration and Plate Count | Quantifies viable microorganisms by filtration, membrane transfer to growth media, and colony enumeration after incubation. |
| Sterility | Direct Inoculation into Culture Media | Confirms absence of viable microorganisms by incubating sample in fluid thioglycollate and soybean-casein digest media for 14 days. |
Technical Specifications of HUWENTOXIN IV
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15.0° to -25.0° (c=1, in 0.1N HCl) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of HUWENTOXIN IV
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of HUWENTOXIN IV
Industrial HUWENTOXIN IV Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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