Mesity aceti acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 52629-46-6 |
| Product name | Mesity aceti acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Mesity aceti acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Mesity aceti acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Mesity aceti acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of active pharmaceutical ingredients such as agomelatine | Used in organic synthesis |
| Chemical Synthesis | Used to construct complex organic molecular structures with biological activity | Applied in organic synthesis |
Manufacturing Quality Control of Mesity aceti acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity and Assay | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reversed-phase column with methanol/water or acetonitrile/water (containing 0.1% formic acid) as mobile phase. Detection is performed using a UV detector (wavelength 220–254 nm). Quantification is achieved via external or internal standard methods, enabling accurate determination of the active ingredient content and impurity levels. |
| Impurity Profile Analysis | High-Performance Liquid Chromatography (HPLC-UV/DAD) | Employs a gradient elution program to separate potential structurally related impurities (e.g., unreacted starting materials, oxidation products, isomers). The DAD detector provides spectral data to assist in impurity identification, complying with ICH Q3B guidelines. |
| Residual Solvent Testing | Gas Chromatography (GC-FID/MS) | Headspace or direct injection is used, with separation on a capillary column (e.g., DB-624) to detect common organic solvents (e.g., methanol, ethanol, ethyl acetate, DMF). Quantification is performed using FID detection, meeting ICH Q3C standards for controlling process-related residual solvents. |
| Moisture Content | Karl Fischer Titration | Measures trace moisture in samples using coulometric or volumetric methods. Suitable for solid active pharmaceutical ingredients (APIs), ensuring moisture content meets pharmacopeial requirements (typically ≤0.5%) to prevent hydrolysis or changes in crystalline form that could affect stability. |
| Melting Point Determination | Melting Point Apparatus | A digital melting point apparatus is used to determine the melting temperature range of the sample (literature value approximately 120–125°C). This test serves as a preliminary identification and purity assessment; a narrow melting range (≤2°C) indicates high purity. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (¹H-NMR / ¹³C-NMR) | Using DMSO-d₆ or CDCl₃ as solvent, characteristic proton signals (e.g., methyl singlet on aromatic ring, methylene singlet) and carbon signals are analyzed to confirm molecular structure, verify the target compound, and rule out isomer contamination. |
| Infrared Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Characteristic functional group absorption peaks (e.g., broad O-H stretch of carboxylic acid ~3000 cm⁻¹, C=O stretch ~1690 cm⁻¹, aromatic C=C ~1600 cm⁻¹) are obtained via KBr pellet or ATR method, used for qualitative identification and batch-to-batch consistency comparison. |
| Heavy Metals and Inorganic Impurities | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, levels of heavy metals such as lead, cadmium, mercury, arsenic, and copper are measured, complying with ICH Q3D or pharmacopeial limits (e.g., Pb ≤10 ppm) to ensure product safety. |
| Polymorphic Form Analysis (if applicable) | X-Ray Powder Diffraction (XRPD) | If polymorphism is a concern, XRPD patterns are compared with reference standards to confirm consistency of the drug substance's crystal form, which can influence solubility and bioavailability. |
| Inorganic Ions (e.g., Chloride, Sulfate) | Ion Chromatography (IC) | Detects inorganic anions (e.g., Cl⁻, SO₄²⁻) potentially introduced during manufacturing. Suppressed ion chromatography offers high sensitivity and complies with pharmacopeial requirements for inorganic impurity control. |
Technical Specifications of Mesity aceti acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 128.0 - 132.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Acid Value (mg KOH/g) | 175 - 185 mg KOH/g |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic mild fatty odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Mesity aceti acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of Mesity aceti acid
Industrial Mesity aceti acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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