China Factory Direct
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| CAS number | 52833-93-9 |
| Product name | 2-Amino-5-chloropyridine-3-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Used as a key intermediate in multistep organic synthesis to prepare biologically active pyridine-based compounds |
| Agrochemicals | Intermediate for insecticides or herbicides | Applied in the synthesis of novel nitrogen-containing heterocyclic agrochemicals, enabling construction of the active molecular scaffold via coupling reactions |
| Fine Chemicals | Organic synthesis reagent | Employed in laboratory-scale synthesis of complex pyridine derivatives, participating in reactions such as Suzuki coupling and amidation |
| Research | Compound for chemical research | Utilized as a functionalized pyridine carboxylic acid derivative in fundamental research for new drug development and materials science |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and detection of structurally related impurities (e.g., starting materials, intermediates, isomers) using gradient HPLC/UV or hyphenated UPLC-MS for identification and quantification. |
| Residual Solvents | GC-FID or GC-MS | Headspace gas chromatography with flame ionization detection or mass spectrometry to quantify residual organic solvents (e.g., methanol, ethyl acetate, DMF) per ICH Q3C guidelines. |
| Heavy Metals (Total) | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, As, Hg, Ni) after acid digestion, based on atomic emission intensity at element-specific wavelengths. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Quantification of inorganic chloride ions via suppressed IC conductivity detection or argentometric titration using silver nitrate and potentiometric endpoint detection. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical determination of water content based on the stoichiometric reaction of iodine with water in anhydrous methanol/pyridine medium. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled ignition at 700–800 °C following sulfuric acid treatment. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to determine volume-based particle size distribution (D10, D50, D90). |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Optical Rotation | Polarimetry | Measurement of specific rotation at specified wavelength (e.g., 589 nm) and temperature to assess chiral purity (if applicable; note: compound is achiral, but method included for batch consistency verification of potential chiral contaminants). |
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 182–186 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.