China Factory Direct
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| CAS number | 529-84-0 |
| Product name | 4-METHYLESCULETIN |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Antioxidant and anti-inflammatory activity studies | Used as a natural product analog in drug screening and structural optimization |
| Cosmetics | Skin protectant and antioxidant additive | Incorporated into skincare formulations to enhance photoprotection against skin aging |
| Biochemical Research | Fluorescent probe and enzyme inhibitor studies | Employed in vitro to evaluate inhibitory effects on specific enzymes |
| Phytochemistry | Natural product extraction and identification | Isolated from plants (e.g., Rutaceae, Apiaceae) as a marker for secondary metabolites |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies 4-methylumbelliferone by reversed-phase HPLC with UV detection at ~320 nm, using external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., umbelliferone, methylated by-products) via gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures trace organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration based on the iodine-sulfur dioxide reaction in pyridine-free reagent. |
| Heavy Metals | ICP-OES | Quantifies total heavy metals (Pb, Cd, Hg, As, Ni) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after combustion with sulfuric acid treatment and high-temperature incineration, followed by weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against defined standards under controlled lighting conditions. |
| Loss on Drying | Thermogravimetric Analysis | Measures mass loss upon heating at 105 C for 2 hours, reflecting volatile components and residual moisture. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to confirm chiral purity and identity (though compound is achiral, used for batch consistency). |
| pH of Aqueous Suspension | pH Meter | Determines pH of a standardized suspension (e.g., 1% w/v in water) to detect acidic/basic degradation products or residual reagents. |
| Test Item | Specification |
|---|---|
| Appearance | Gray powder |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 215–219 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.