(R)-(-)-2-Chloromandelic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 52950-18-2 |
| Product name | (R)-(-)-2-Chloromandelic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-(-)-2-Chloromandelic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-(-)-2-Chloromandelic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-(-)-2-Chloromandelic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug intermediates (e.g., for antidepressants and cardiovascular agents) | Used in asymmetric synthesis and resolution processes |
| Agriculture | Chiral precursors to active ingredients in agrochemicals (e.g., herbicides and fungicides) | Applied in catalytic hydrogenation and esterification reactions |
| Chemical Research | Chiral ligands or catalysts for asymmetric synthesis reactions | Employed in organic synthesis and crystallization-based resolution |
| Materials Science | Chiral building blocks for liquid crystal materials or functional polymer monomers | Utilized in polymerization and functional group modification |
Manufacturing Quality Control of (R)-(-)-2-Chloromandelic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Chemical Purity | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase C18 column with a UV detector (e.g., 210–220 nm); quantification of the main component is performed based on retention time and peak area to assess chemical purity. |
| Enantiomeric Purity (Optical Purity) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employs chiral stationary phase columns (e.g., Chiralpak AD-H, OD-H, etc.) to separate R and S enantiomers; enantiomeric excess (ee value) is calculated to ensure R-configuration predominates. |
| Water Content | Karl Fischer Titration | According to pharmacopoeial standards, coulometric or volumetric methods are used to determine water content, controlled within specified limits (typically ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace or direct injection with an FID detector; detects organic solvents such as ethanol, toluene, and ethyl acetate in accordance with ICH Q3C guidelines. |
| Melting Point | Capillary Melting Point Apparatus | Determines the temperature range at which the substance transitions from solid to liquid; used for preliminary assessment of purity and crystalline form consistency (literature value: approximately 118–120°C). |
| Specific Rotation | Polarimeter Method | Measures optical rotation at a specified wavelength (e.g., sodium D-line, 589 nm) and concentration; calculates specific rotation [α] to verify chiral configuration and optical activity. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Following pharmacopoeial general chapters, samples are digested and analyzed for residual elements such as lead, arsenic, cadmium, and mercury, ensuring compliance with safety limits (e.g., ≤10–20 ppm). |
| Loss on Drying | Oven Drying Method | Sample is dried to constant weight at a specified temperature (e.g., 105°C) under vacuum; mass loss is measured to reflect total volatile substances and moisture. |
| Related Substances (Impurities) | HPLC with Gradient Elution | Employs a gradient elution program to separate and detect synthetic by-products and degradation products; quantification is performed via area normalization or external standard method, controlling limits for individual and total impurities. |
| pH Value (Solution) | pH Meter Method | Aqueous solution at a specified concentration (e.g., 1% w/v) is prepared and pH is measured using a calibrated pH meter to ensure the acidic-basic environment meets process or formulation requirements (typically weakly acidic). |
Technical Specifications of (R)-(-)-2-Chloromandelic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Optical Rotation | -126.0 to -123.0 deg (c=1, in CHCl3) |
| Melting Point | 78.0 to 82.0 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-(-)-2-Chloromandelic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-(-)-2-Chloromandelic acid
Safety Information of (R)-(-)-2-Chloromandelic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-(-)-2-Chloromandelic acid
Industrial (R)-(-)-2-Chloromandelic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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