China Factory Direct
|
|
| CAS number | 53-59-8 |
| Product name | Triphosphopyridine nucleotide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Acts as a coenzyme in multiple metabolic processes, including fatty acid synthesis and drug metabolism | NADP+ forms enzyme-bound complexes in vivo to catalyze redox reactions |
| Cosmetics | Anti-aging ingredient that promotes skin cell metabolism | Applied topically to the skin surface to activate NADPH-dependent enzymes and improve skin condition |
| Food Industry | Food additive used to enhance nutritional value or serve as an antioxidant | Incorporated into food products during manufacturing to extend shelf life via its antioxidant properties |
| Scientific Research | Lab reagent for biochemical experiments and studies | Added to experimental systems as a reference standard or used to assess the activity and concentration changes of other compounds |
| Dietary Supplements | Nutritional supplement supporting energy production and cellular repair | Administered orally (e.g., in capsule form) and converted to NADPH in the body to modulate physiological functions |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Testing | High-Performance Liquid Chromatography (HPLC) | Separates samples using reversed-phase or ion-pair chromatographic columns, with UV detection (e.g., at 260 nm) to quantify the main peak area and calculate purity percentage. Effective in distinguishing NADP⁺ from its degradation products (e.g., NAD⁺, NMN, etc.). |
| Content Determination | Ultraviolet-Visible Spectrophotometry | Utilizes the characteristic absorption peak of NADP⁺ at specific wavelengths (e.g., 259–260 nm), calculating concentration based on molar absorptivity (ε ≈ 18,000 L·mol⁻¹·cm⁻¹). Background interference must be corrected. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H-NMR and ³¹P-NMR are used to analyze chemical shifts of hydrogen and phosphorus atoms, verifying structural integrity and confirming characteristic peaks associated with phosphate groups, nicotinamide ring, adenine moiety, etc. |
| Molecular Weight Confirmation | Mass Spectrometry (MS), such as ESI-MS or MALDI-TOF | Electrospray ionization mass spectrometry accurately determines the molecular ion peak ([M-H]⁻ m/z ≈ 743.4), confirming molecular formula and matching theoretical molecular weight. |
| pH Value | pH Meter Measurement | Sample is dissolved into a specified concentration aqueous solution (e.g., 1% w/v), then directly measured using a calibrated pH meter to ensure compliance with pharmacopoeial or standard specifications (typically pH 6.0–8.0). |
| Loss on Drying | Gravimetric Drying Method or Karl Fischer Water Titration | Drying method: Dry at 105°C until constant weight, then calculate loss percentage; Karl Fischer titration provides higher accuracy for measuring bound water content, suitable for thermally unstable samples. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, ICP-MS simultaneously detects multiple heavy metals (e.g., Pb, As, Cd, Hg) with high sensitivity, meeting ICH Q3D requirements. |
| Microbial Limits | Pharmacopoeial Microbial Testing Methods (e.g., USP <61>/<62>) | Uses membrane filtration or plate count methods to test total aerobic bacteria, molds/yeasts, and control organisms (e.g., Escherichia coli, Salmonella spp.), ensuring sterility or compliance with non-sterile product standards. |
| Endotoxin (for Injectable Grades) | Limulus Amebocyte Lysate (LAL) Assay | Utilizes lysate from horseshoe crab blood to induce coagulation upon contact with endotoxins; quantified via colorimetric or turbidimetric methods, ensuring endotoxin levels remain below specified limits (e.g., <0.25 EU/mg). |
| Related Substances / Impurity Analysis | HPLC-UV or LC-MS Coupling | Gradient elution HPLC separates potential impurities (e.g., oxidation products, synthetic by-products, degradation compounds); LC-MS aids in identification. Quantification performed using area normalization or external standard methods. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -20.0° to -24.0° (c=1, in water) |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.