China Factory Direct
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| CAS number | 53-84-9 |
| Product name | β-Nicotinamide adenine dinucleotide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Coenzyme involved in cellular energy metabolism (e.g., glycolysis, tricarboxylic acid cycle, oxidative phosphorylation) | Added as an active ingredient to injectables, oral formulations, or cell culture media |
| Food Industry | Vitamin B3 (niacin) fortificant and nutritional supplement | Added to infant formula, sports drinks, nutritionally fortified flour, and other food products |
| Cosmetics | Enhancer of skin cell energy metabolism; antioxidant; improves skin quality | Formulated into topical anti-aging serums, moisturizing creams, and face masks |
| Biological Assays | Key component in biochemical assay kits for dehydrogenase activity detection (e.g., lactate dehydrogenase, glucose-6-phosphate dehydrogenase) | Serves as a substrate or cofactor in enzymatic reactions within colorimetric or fluorometric assay systems |
| Research | Standard coenzyme reagent for cell biology and metabolic studies | Used in in vitro enzyme kinetics assays, mitochondrial function assessment, and NAD+/NADH ratio determination |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Assay | High-Performance Liquid Chromatography (HPLC-UV/DAD) | Separation of NAD⁺/NADH using a reverse-phase chromatography column, with quantification via UV detector at 260 nm; offers high sensitivity and excellent reproducibility. |
| Purity Analysis | HPLC-ELSD or HPLC-MS | Evaporative Light Scattering Detection (ELSD) or Mass Spectrometry (MS) can identify impurity peaks and assess main component purity, particularly effective for detecting impurities without UV absorption. |
| Related Substances / Impurity Detection | HPLC-UV or UPLC-MS/MS | Utilizes high-resolution chromatography coupled with mass spectrometry to identify and quantify degradation products (e.g., nicotinamide, AMP, ADP) and related impurities. |
| Oxidation-Reduction Ratio (NAD⁺/NADH) | Enzymatic Cycling Method + Spectrophotometry | Utilizes lactate dehydrogenase or alcohol dehydrogenase-catalyzed reactions; measures absorbance changes at 340 nm to determine NAD⁺ and NADH concentrations separately and calculate their ratio. |
| pH Value | pH Meter Method | Measures pH of aqueous solutions using a standardized pH electrode to ensure the product remains within the stable range (typically 6.0–8.0). |
| Loss on Drying | Drying Method (105°C to Constant Weight) | Dries the sample at a specified temperature until constant weight is achieved, then calculates moisture and volatile content to assess stability. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detects residual heavy metal elements such as lead, arsenic, cadmium, and mercury using atomic absorption or inductively coupled plasma mass spectrometry, ensuring compliance with pharmacopeial limits. |
| Microbial Limits | Plate Count Method / Membrane Filtration Method | Performs total aerobic microbial count, mold, and yeast enumeration according to Chinese Pharmacopoeia or USP standards to control microbial contamination risk. |
| Endotoxins | Limulus Amebocyte Lysate (LAL) Assay | Utilizes the coagulation reaction between LAL and endotoxins to quantitatively detect bacterial endotoxin levels, suitable for quality control of injectable-grade raw materials. |
| Specific Rotation | Polarimeter Method | Measures optical rotation of a specific concentration solution under sodium light (589 nm) to verify molecular configuration consistency, serving as an auxiliary indicator for identification and purity. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -35.0 to -28.0 deg (c=1, H2O) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.