4-Hydroxy-3,5-dimethoxycinnamic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 530-59-6 |
| Product name | 4-Hydroxy-3,5-dimethoxycinnamic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Hydroxy-3,5-dimethoxycinnamic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Hydroxy-3,5-dimethoxycinnamic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Hydroxy-3,5-dimethoxycinnamic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Natural antioxidant and anti-inflammatory agent | Applied in anti-aging and anti-inflammatory drug development through free radical scavenging and suppression of pro-inflammatory factor expression. |
| Pharmaceutical Industry | Chemotherapy sensitizer | Used to reverse multidrug resistance (MDR) in tumor cells and enhance the efficacy of chemotherapeutic agents such as doxorubicin. |
| Pharmaceutical Industry | Neuroprotective agent | Applied in research on neurodegenerative disorders such as Alzheimer’s disease via acetylcholinesterase inhibition or mitigation of oxidative stress. |
| Chemical Industry | Organic synthesis intermediate | Used to synthesize derivatives such as sinapamide and sinapate esters, which are further applied in materials or pharmaceuticals. |
| Chemical Industry | Bio-based chemical conversion | Converted into high-value platform chemicals such as vanillic acid and catechol via microbial fermentation or chemical catalysis. |
| Food Industry | Food preservative and freshness enhancer | Incorporated into food packaging materials or directly added to food products to extend shelf life, leveraging its antimicrobial properties. |
| Food Industry | Food antioxidant additive | Applied as a natural antioxidant to prevent oxidative rancidity in lipid-rich food products. |
| Personal Care Industry | Ultraviolet (UV) absorber | Formulated into sunscreen cosmetics to absorb UV radiation—particularly in the UVB range—and reduce photodamage. |
| Personal Care Industry | Skin-lightening active ingredient | Applied in skin-lightening product development through tyrosinase inhibition and subsequent reduction of melanin synthesis. |
| Agricultural Sector | Plant growth regulator | Involved in plant physiological metabolism to induce defense responses, thereby promoting growth or enhancing stress tolerance. |
| Materials Industry | Functional material modifier | Applied to modify lignin-based polymeric materials, improving thermal stability or UV-shielding performance. |
Manufacturing Quality Control of 4-Hydroxy-3,5-dimethoxycinnamic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Assay | High-Performance Liquid Chromatography (HPLC) | A C18 reversed-phase column is used with methanol-water or acetonitrile-water (containing a small amount of acid such as phosphoric acid or formic acid) as the mobile phase for gradient or isocratic elution. Detection is performed at 320–330 nm using a UV detector, and sinapic acid content is quantified by external or internal standard methods. This method offers high sensitivity and good reproducibility, and is suitable for quantitative analysis of sinapic acid in raw pharmaceutical materials and plant extracts. |
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Sinapic acid exhibits characteristic absorption peaks near 290 nm and 320 nm. Preliminary identification is achieved by comparing the UV absorption spectra of the test sample with that of the reference standard. This method is simple and commonly used for rapid screening. |
| Purity Test | High-Performance Liquid Chromatography (HPLC) | Based on the assay method, sample purity is evaluated by assessing peak symmetry, theoretical plate number, and the number of impurity peaks. Diode array detection (DAD) can be combined to analyze peak purity and confirm whether the main component contains structurally similar impurities (e.g., other phenolic acids). |
| Structural Confirmation | Liquid Chromatography-Mass Spectrometry (LC-MS) | Couples HPLC with mass spectrometry to confirm the structure of sinapic acid based on the molecular ion peak ([M-H]⁻ at m/z ~223) and fragment ion information. Suitable for qualitative analysis of the target compound in complex matrices and for metabolic studies. |
| Simultaneous Multi-component Analysis | Ultra-Performance Liquid Chromatography (UPLC) | Uses sub-2 μm particle-packed columns to achieve rapid separation under high pressure, enabling simultaneous detection of sinapic acid and other phenolic acid components (e.g., ferulic acid, caffeic acid). Offers improved analytical efficiency and resolution, making it ideal for comprehensive quality control of plant extracts. |
| Residual Solvent Testing | Gas Chromatography (GC) | If organic solvents (e.g., methanol, ethanol) are used during the preparation of sinapic acid, gas chromatography must be employed to test for residual solvents in accordance with pharmacopoeial requirements, ensuring compliance with safety limits. |
Technical Specifications of 4-Hydroxy-3,5-dimethoxycinnamic acid
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Acid Value (mg KOH/g) | 180–195 mg KOH/g |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Hydroxy-3,5-dimethoxycinnamic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Hydroxy-3,5-dimethoxycinnamic acid
Safety Information of 4-Hydroxy-3,5-dimethoxycinnamic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Hydroxy-3,5-dimethoxycinnamic acid
Industrial 4-Hydroxy-3,5-dimethoxycinnamic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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