4-Amino-6-chloropyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5305-59-9 |
| Product name | 4-Amino-6-chloropyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Amino-6-chloropyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Amino-6-chloropyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Amino-6-chloropyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of herbicide and fungicide intermediates | Ammonolysis of chloropyrimidine with aqueous ammonia under elevated temperature and pressure to produce 4-amino-6-chloropyrimidine |
| Pharmaceuticals | Synthesis of antiviral and anticancer drug intermediates | Used as a synthetic precursor for pyrimidine nucleoside analogues to construct drug molecular scaffolds |
| Polymers | Functional monomer for specialty resin synthesis | Incorporated into polymer chains via condensation polymerization or grafting reactions to enhance material properties |
| Dyes and Pigments | Synthesis of nitrogen-containing heterocyclic dye intermediates | Employed as a coupling component in diazotization-coupling reactions for azo dye production |
| Analytical Reagents | Reference standard or certified reference material | Used as a calibration standard in analytical techniques such as HPLC and GC-MS |
Manufacturing Quality Control of 4-Amino-6-chloropyrimidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, DMF) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using plasma emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential inflection corresponding to AgCl precipitation. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined saturated aqueous suspension (e.g., 1% w/v) using calibrated pH electrode. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by sulfuric acid treatment and weighing of residual inorganic ash. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using light scattering principles to derive D10, D50, D90 values. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after standardized mechanical tapping per USP <616>. |
Technical Specifications of 4-Amino-6-chloropyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 128–132 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Amino-6-chloropyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Amino-6-chloropyrimidine
Packaging of 4-Amino-6-chloropyrimidine
Industrial 4-Amino-6-chloropyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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