N-Boc-4-Hydroxyphenyl-DL-glycine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 53249-34-6 |
| Product name | N-Boc-4-Hydroxyphenyl-DL-glycine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N-Boc-4-Hydroxyphenyl-DL-glycine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N-Boc-4-Hydroxyphenyl-DL-glycine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N-Boc-4-Hydroxyphenyl-DL-glycine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key intermediate in peptide drug synthesis | Serves as an amino acid building block; after Boc deprotection, applied in solid-phase or liquid-phase peptide synthesis (SPPS/LPPS) to construct peptide chains containing the 4-hydroxyphenylglycine residue |
| Pharmaceutical Chemicals | Precursor for chiral drug synthesis | Optically pure N-Boc-D-4-hydroxyphenylglycine or N-Boc-L-4-hydroxyphenylglycine is prepared via chiral resolution and used in the synthesis of single-enantiomer drugs |
| Pharmaceutical Chemicals | Raw material for antibiotic and cardiovascular drug synthesis | Applied in synthesizing drug molecules containing the 4-hydroxyphenylglycine moiety, such as certain β-lactam antibiotics or angiotensin-converting enzyme inhibitor (ACEI) analogues |
| Research Reagents | Organic synthesis and biochemical research | Used in studies of peptide folding mechanisms, synthesis of protease substrates, and design and synthesis of novel heterocyclic compounds |
Manufacturing Quality Control of N-Boc-4-Hydroxyphenyl-DL-glycine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-254 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separates D and L enantiomers on a chiral stationary phase and quantifies enantiomeric excess via peak area ratio. |
| Residual Solvents | GC-FID | Detects and quantifies common organic solvents (e.g., methanol, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures trace water content via coulometric or volumetric titration using iodine-sulfur dioxide reaction in pyridine/methanol medium. |
| Heavy Metals | ICP-OES | Determines total heavy metal content (Pb, Cd, Hg, As, etc.) by plasma excitation and elemental emission intensity measurement. |
| Residual Palladium | ICP-MS | Quantifies trace palladium catalyst residues using inductively coupled plasma mass spectrometry for high sensitivity and specificity. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., de-Boc, hydrolyzed, dimeric species) using gradient HPLC-UV. |
| Optical Rotation | [alpha]D Measurement | Measures specific optical rotation at 20 C using sodium D-line (589 nm) to confirm chiral integrity and batch consistency. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines pH of a defined aqueous suspension or solution using calibrated glass electrode and pH meter. |
| Loss on Drying | Gravimetric Heating | Measures volatile content by weight loss after drying at specified temperature (e.g., 105 C) under vacuum or nitrogen. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or dispersed powder particle size distribution using Mie scattering theory and laser diffraction instrumentation. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
Technical Specifications of N-Boc-4-Hydroxyphenyl-DL-glycine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | -1.0° to +1.0° (c=1, in 1M HCl) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N-Boc-4-Hydroxyphenyl-DL-glycine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N-Boc-4-Hydroxyphenyl-DL-glycine
Safety Information of N-Boc-4-Hydroxyphenyl-DL-glycine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N-Boc-4-Hydroxyphenyl-DL-glycine
Industrial N-Boc-4-Hydroxyphenyl-DL-glycine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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