2-Acetylamino-4-methylpyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5327-32-2 |
| Product name | 2-Acetylamino-4-methylpyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Acetylamino-4-methylpyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Acetylamino-4-methylpyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Acetylamino-4-methylpyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing the anti-tuberculosis drug ethambutol | Undergoes N-alkylation with 1-bromo-2-methylpropane, followed by hydrolysis and resolution to produce ethambutol |
| Pharmaceuticals | Used in synthesizing other pyridine-containing bioactive molecules (e.g., kinase inhibitor lead compounds) | Serves as a nitrogen-containing heteroaromatic building block in transition metal-catalyzed reactions, including Suzuki coupling and Buchwald–Hartwig amination |
| Pesticides | Potential structural motif for insecticides/fungicides (under research) | Functionalized at the 4-methyl or 2-acetamido position to introduce pharmacophores, enabling construction of novel heterocyclic agrochemicals |
Manufacturing Quality Control of 2-Acetylamino-4-methylpyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode array detection; relative retention times and UV spectra support qualification. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using isotopic detection for high sensitivity and specificity. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on an anion-exchange column with suppressed conductivity detection; quantified via external calibration. |
| Sulfated Ash | Gravimetric Analysis | Sample incineration at 500-600 C followed by sulfuric acid treatment and final ash weighing to determine inorganic residue content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range where solid transforms to liquid, indicating purity and identity. |
| Appearance | Visual Inspection | Assessment under controlled white light against standard color/opacity references; detects discoloration, particulates, or phase separation. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode; reflects acidic/basic impurity profile. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Weight loss measured upon heating to 105 C under nitrogen; indicates volatile content including residual solvents and moisture. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light; confirms chiral integrity and absence of racemization during synthesis or storage. |
Technical Specifications of 2-Acetylamino-4-methylpyridine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 62.0–65.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Acetylamino-4-methylpyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Acetylamino-4-methylpyridine
Safety Information of 2-Acetylamino-4-methylpyridine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Acetylamino-4-methylpyridine
Industrial 2-Acetylamino-4-methylpyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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