China Factory Direct
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| CAS number | 533-67-5 |
| Product name | 2-Deoxy-D-ribose |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceuticals | Key intermediate in the synthesis of antiviral drugs (e.g., nucleoside reverse transcriptase inhibitors such as zidovudine and stavudine) | Deoxynucleoside structure is constructed via chemical or enzymatic coupling of 2-deoxy-D-ribose with a nucleobase, followed by multi-step modifications to yield the target drug |
| Biotechnology | Synthesis of DNA probes, primers, and modified oligonucleotides | Serves as the initiating sugar unit in solid-phase synthesis, participating in phosphodiester bond formation to assemble deoxyoligonucleotides of defined sequence |
| Research | Model compound for studying DNA structure, function, and damage repair mechanisms | Used to prepare oligonucleotides containing specific 2-deoxyribose derivatives that mimic oxidative or alkylative damage sites |
| Diagnostics | Preparation of labeled nucleotide analogs for nucleic acid detection or genotyping | 2-Deoxy-D-ribose is coupled with fluorescent or biotin-labeled nucleobases to synthesize detectable nucleotide probes |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with the standard spectrum to confirm the presence of characteristic functional groups (e.g., hydroxyl, aldehyde) of 2-deoxy-D-ribose. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Use ¹H NMR to measure chemical shifts and coupling constants of hydrogen atoms in the sample, and verify structural characteristics by comparison with a reference spectrum. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employ a reversed-phase or hydrophilic interaction chromatography column to separate 2-deoxy-D-ribose using an appropriate mobile phase (e.g., acetonitrile-water system), followed by quantification via UV or refractive index detection, and calculate concentration using an external standard method. |
| Gas Chromatography (GC, after derivatization) | Derivatize 2-deoxy-D-ribose (e.g., via silylation or acetylation), then separate using a capillary GC column and detect/quantify with a flame ionization detector (FID). | |
| Related Substances / Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Use gradient or isocratic elution to separate the main component from potential impurities (e.g., dehydration or oxidation products). Impurity levels are controlled using peak area normalization or a main component self-reference method with correction factors. |
| Specific Optical Rotation | Polarimetry | Measure the optical rotation of the sample solution at a specified temperature and wavelength (typically the sodium D line, 589 nm), and calculate the specific optical rotation to assess optical purity and configurational consistency. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Weight Method | Dry the sample at 105°C until constant weight is achieved, and determine the percentage weight loss to evaluate moisture and volatile content. |
| Sulfated Ash | Residue on Ignition Test | Ignite the sample at high temperature (approximately 700–800°C), then weigh the residual inorganic matter to control total inorganic impurities. |
| pH Value | pH Meter Method | Prepare an aqueous solution of defined concentration (e.g., 1% w/v), and measure pH using a calibrated pH meter to ensure it falls within the specified range (typically near neutral). |
| Water Content | Karl Fischer Titration | Use volumetric or coulometric Karl Fischer titration for specific determination of water content; suitable for heat-sensitive samples or those containing crystalline water. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by NMR) |
| Water Content (KF) | <=0.5% |
| Melting Point | 83-87°C |
| Optical Rotation | -54.0 to -58.0° (c=1, in H2O) |
| Total Impurities | <=2.0% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.