China Factory Direct
|
|
| CAS number | 5330-71-2 |
| Product name | 4-(phenylmethoxycarbonylamino)benzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as an intermediate in the synthesis of angiotensin-converting enzyme (ACE) inhibitors, such as enalapril | Constructs the drug molecule backbone via organic synthesis reactions including acylation and condensation |
| Chemical Research | Used as a protecting group reagent or structural building block in peptide and small-molecule synthesis | Introduces the benzyloxycarbonyl (Cbz) group to protect amines during solid-phase or solution-phase synthesis; subsequent deprotection enables target molecule assembly |
| Biochemistry | Used to prepare amino-protected probes or labeling agents for protein/peptide structural studies | After conjugation with biomolecules, analyzed and detected using chromatographic or mass spectrometric techniques |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities using gradient HPLC-UV; identification and quantification against reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, toluene) based on retention time and peak area. |
| Heavy Metals | ICP-OES | Multi-element determination of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using plasma optical emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-750 C followed by sulfuric acid treatment and final weighing of inorganic residue. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent; water reacts stoichiometrically to generate endpoint current or voltage change. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of crystalline solid against defined standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dry or dispersed state using Mie scattering theory and laser diffraction optics. |
| Specific Optical Rotation | Polarimetry | Determination of chiral purity using sodium D-line light; rotation angle measured relative to path length and concentration. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined saturated aqueous suspension using calibrated pH electrode and temperature compensation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 192–196°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Acid Value (mg KOH/g) | 320–340 mg KOH/g |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.