2-AMINO-3-CHLOROBENZONITRILE Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 53312-77-9 |
| Product name | 2-AMINO-3-CHLOROBENZONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 2-AMINO-3-CHLOROBENZONITRILE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-AMINO-3-CHLOROBENZONITRILE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-AMINO-3-CHLOROBENZONITRILE
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the insecticide flupyradifurone | Functionalized via diazotization–Sandmeyer reaction or direct chlorination–ammonolysis to construct the neonicotinoid insecticide core structure from 2-amino-3-chlorobenzonitrile |
| Pharmaceuticals | Used to synthesize quinazoline- and benzimidazole-based drug candidates with antitumor and anti-inflammatory activity | Serves as an aromatic building block bearing both chloro and cyano functionalities; participates in cyclization reactions (e.g., condensation with o-phenylenediamine to yield benzimidazole derivatives) or palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce pharmacophores |
| Dyes | Intermediate for azo dyes and reactive dyes, enhancing lightfastness and fixation performance | After diazotization, coupled with phenols or aromatic amines to form chloro–cyano-substituted azo structures; alternatively, the cyano group is hydrolyzed to carboxylic acid to produce reactive dye intermediates |
Manufacturing Quality Control of 2-AMINO-3-CHLOROBENZONITRILE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~220–254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and quantification of impurities (e.g., 2-amino-benzonitrile, 3-chloro-2-nitrobenzonitrile) using gradient elution and UV/MS detection. |
| Residual Solvents | GC-FID or GC-MS | Headspace GC analysis with flame ionization or mass spectrometric detection to quantify solvents (e.g., methanol, toluene, DMF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample in anhydrous medium. |
| Heavy Metals | ICP-MS or AAS (after acid digestion) | Quantification of elemental impurities (e.g., Pb, Cd, As, Hg) following microwave-assisted nitric/hydrogen peroxide digestion. |
| Chloride Ion Impurity | Ion Chromatography (IC) or Potentiometric Titration | Separation and quantification of Cl⁻ by IC with conductivity detection, or argentometric titration using AgNO₃ and potentiometric endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated digital apparatus; correlates with crystalline purity and identity. |
| Appearance & Color | Visual Inspection / Hazen (APHA) Color Scale | Subjective visual assessment against water standard; color quantified spectrophotometrically at 455 nm per APHA method. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of inorganic ash content after controlled high-temperature (700–800 °C) ignition and weighing of residual residue. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 20 °C using sodium D-line (589 nm); confirms chiral integrity (though compound is achiral, used for batch consistency). |
Technical Specifications of 2-AMINO-3-CHLOROBENZONITRILE
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (GC) |
| Melting Point | 78–82°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 2-AMINO-3-CHLOROBENZONITRILE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-AMINO-3-CHLOROBENZONITRILE
Packaging of 2-AMINO-3-CHLOROBENZONITRILE
Industrial 2-AMINO-3-CHLOROBENZONITRILE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply