4-Methyl-3-nitroacetophenone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5333-27-7 |
| Product name | 4-Methyl-3-nitroacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Methyl-3-nitroacetophenone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Methyl-3-nitroacetophenone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Methyl-3-nitroacetophenone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antidepressant drugs | Used as an intermediate in reduction and condensation reactions |
| Pesticides | Herbicide production | Undergoes substitution reactions to generate target compounds |
| Dyes | Preparation of acid dyes | Introduces specific functional groups via coupling reactions |
| Fragrances | Synthesis of fragrance intermediates | Hydrogenation and esterification reactions yield downstream products |
| Medical diagnostic reagents | Manufacture of developing agents | Participates in nitro reduction and amidation reactions |
Manufacturing Quality Control of 4-Methyl-3-nitroacetophenone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances (Impurities) | HPLC-UV or GC-FID | Separation and quantification of structurally related impurities (e.g., unreacted 3-nitro-4-methylacetophenone precursors, isomers, degradants) using retention time matching and response factor correction. |
| Moisture Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Incineration at 700–800 °C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after microwave-assisted acid digestion, based on atomic emission intensities at element-specific wavelengths. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid-to-liquid phase transition occurs, indicating crystallinity and presence of impurities. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Anion separation and quantification (IC) or argentometric titration with AgNO₃ endpoint detection for soluble chloride impurities. |
| Organic Volatile Impurities (e.g., acetone, toluene) | GC-FID | Headspace or direct injection GC analysis with flame ionization detection to identify and quantify residual solvents per ICH Q3C guidelines. |
| Appearance and Color | Visual Inspection & APHA Color Scale | Subjective assessment of physical state (crystalline powder) and quantitative color measurement against platinum-cobalt standards. |
| Acid Value | Acid-Base Titration (NaOH, phenolphthalein) | Neutralization of acidic impurities (e.g., residual nitric acid or oxidation by-products) with standardized sodium hydroxide solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to determine volumetric particle size distribution in dry or dispersed state. |
| Bulk Density | Gravimetric Volumetric Method | Mass of material divided by its freely settled volume in a calibrated cylinder, indicating flow and handling properties. |
| Loss on Drying (LOD) | Thermogravimetric Analysis (TGA) or Oven Drying | Measurement of mass loss upon heating under controlled conditions (e.g., 105 °C, 2 h), reflecting volatile content including residual solvents and moisture. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, confirming absence of chiral contaminants (though compound is achiral, detects optically active impurities). |
Technical Specifications of 4-Methyl-3-nitroacetophenone
| Test Item | Specification |
|---|---|
| Appearance | Cream to yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 52–56°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Methyl-3-nitroacetophenone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Methyl-3-nitroacetophenone
Packaging of 4-Methyl-3-nitroacetophenone
Industrial 4-Methyl-3-nitroacetophenone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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