Tetrahydro-2H-pyran-4-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5337-03-1 |
| Product name | Tetrahydro-2H-pyran-4-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Tetrahydro-2H-pyran-4-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Tetrahydro-2H-pyran-4-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Tetrahydro-2H-pyran-4-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Chiral intermediate for synthesizing antiviral agents and neuroactive compounds | Optically pure tetrahydropyran-4-carboxylic acid is prepared via asymmetric hydrogenation or enzymatic resolution, followed by esterification or amidation to incorporate into drug molecules |
| Agrochemicals | Building block for novel insecticides or fungicides | Condensed with amines to form tetrahydropyran-containing amide active ingredients, purified for formulation preparation |
| Organic Synthesis | Chiral building block for total synthesis of complex natural products | Tetrahydropyran scaffold is constructed via epoxide ring-opening or intramolecular esterification, followed by oxidation or reduction to modulate the carboxylic acid functionality |
| Polymers & Materials | Monomer for synthesizing biodegradable polyesters or polyurethanes | Reacted with diols or diisocyanates via condensation polymerization to yield heterocycle-containing polymers, processed into final forms via melt or solution polymerization |
Manufacturing Quality Control of Tetrahydro-2H-pyran-4-carboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography. |
| Related Substances | HPLC with UV detection | Separation and quantification of structurally similar impurities using gradient elution and UV absorbance at 210 nm. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by gas chromatographic separation and flame ionization detection. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration using iodine generated in situ to react stoichiometrically with water. |
| Acidity (as HCl) | Acid-Base Titration | Neutralization of acidic impurities with standardized sodium hydroxide solution using phenolphthalein or potentiometric endpoint detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue remaining after high-temperature ashing at 700-800 C. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using controlled heating and visual or automated detection. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral molecules in solution at specified concentration and path length. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity pattern to determine size distribution of solid particles in suspension or dry state. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode and pH meter in a standardized aqueous solution. |
Technical Specifications of Tetrahydro-2H-pyran-4-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 128–132°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Odor | Characteristic mild odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Tetrahydro-2H-pyran-4-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Tetrahydro-2H-pyran-4-carboxylic acid
Safety Information of Tetrahydro-2H-pyran-4-carboxylic acid
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of Tetrahydro-2H-pyran-4-carboxylic acid
Industrial Tetrahydro-2H-pyran-4-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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