5,6,7,8-TETRAHYDROQUINOLINONE-5 Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 53400-41-2 |
| Product name | 5,6,7,8-TETRAHYDROQUINOLINONE-5 |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5,6,7,8-TETRAHYDROQUINOLINONE-5
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5,6,7,8-TETRAHYDROQUINOLINONE-5 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5,6,7,8-TETRAHYDROQUINOLINONE-5
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Intermediate for the antiplatelet drug prasugrel | Serves as a key cyclic intermediate in the reaction with fluorinating agents to produce 2-fluoro-7,8-dihydro-6H-quinolin-5-one, a precursor to the prasugrel active pharmaceutical ingredient. |
| Pharmaceutical Chemicals | Building block for novel drug discovery | Undergoes structural modification and functional group transformation via its defined ketone carbonyl and cyclic framework to synthesize quinoline derivatives with potential biological activity. |
| Organic Synthesis | Synthesis of quinoline derivatives | Used in reduction, condensation, or nucleophilic addition reactions to prepare dihydroquinoline or tetrahydroquinoline compounds. |
Manufacturing Quality Control of 5,6,7,8-TETRAHYDROQUINOLINONE-5
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-MS | Multi-element detection of toxic metals (Pb, Cd, Hg, As) after acid digestion, with detection at sub-pptr levels. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of residual inorganic ash after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light and against standard references. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light using sodium D-line (589 nm) to confirm chiral integrity and identity. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue after ignition at 600 C to assess non-volatile inorganic impurities. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per USP <791>. |
Technical Specifications of 5,6,7,8-TETRAHYDROQUINOLINONE-5
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 45–49°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic mild odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5,6,7,8-TETRAHYDROQUINOLINONE-5
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5,6,7,8-TETRAHYDROQUINOLINONE-5
Safety Information of 5,6,7,8-TETRAHYDROQUINOLINONE-5
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5,6,7,8-TETRAHYDROQUINOLINONE-5
Industrial 5,6,7,8-TETRAHYDROQUINOLINONE-5 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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