China Factory Direct
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| CAS number | 53472-18-7 |
| Product name | 5-BROMO-QUINOLIN-8-YLAMINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antiviral drugs, used in the synthesis of HIV protease inhibitors and RNA polymerase inhibitors | Synthesized via cyclization between a triazole ring and a pyrimidine ring; typically involves an acid-catalyzed [3+2] cycloaddition of azides with nitriles, followed by hydrolysis to yield the 7-hydroxy derivative |
| Pharmaceuticals | Building block for kinase inhibitor heterocyclic scaffolds targeting signaling pathways such as PI3K and mTOR | Starting from 7-hydroxy-3H-[1,2,3]triazolo[4,5-d]pyrimidine, pharmacophoric groups are introduced via sulfonylation, alkylation, or amidation for structural optimization |
| Chemical Research | Core structure for fluorescent probes or biolabels | Fluorophores (e.g., fluorescein derivatives) are introduced at the 7-hydroxy position via esterification or etherification for cell imaging and molecular recognition studies |
| Pesticides | Candidate structural motif for novel fungicides or plant growth regulators | Halogen or nitrogen-containing heterocycles are introduced onto the triazolopyrimidine ring via substitution reactions at laboratory scale to evaluate inhibition of fungal hyphal growth |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities relative to the main peak using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-methanol buffer to determine trace water. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion by optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity-based quantification of chloride ions in aqueous extract. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity-based quantification of sulfate ions in aqueous extract. |
| Residue on Ignition | Gravimetric Analysis | Mass measurement of inorganic ash remaining after high-temperature incineration at 700-800 C. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid under controlled heating. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled lighting against standard references. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to calculate volume-based particle size distribution in dispersed sample. |
| Test Item | Specification |
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| Appearance | Light yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 245–249°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.