China Factory Direct
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| CAS number | 5355-68-0 |
| Product name | 1-Isopropyl-4-piperidone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key structural unit in constructing piperidine-based drug scaffolds (e.g., antipsychotics, anticancer agents) via reductive amination or nucleophilic substitution. |
| Pharmaceutical Chemicals | Structure–Activity Relationship (SAR) Studies | Leverages the steric hindrance of the isopropyl group in the design and synthetic optimization of active pharmaceutical ingredients (APIs). |
| Organic Synthesis | Specialty Chemicals Synthesis | Acts as an electrophile in reactions with Grignard or organolithium reagents to prepare derivatized 4-substituted piperidine compounds. |
| Biochemistry | Enzyme Inhibitor Development | Used in synthesizing enzyme inhibitor or receptor antagonist intermediates for screening and synthesis of bioactive molecules. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase chromatography with UV detection at 210 nm, calibrated against reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using gradient HPLC with diode-array detection; peak area comparison to main peak. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., acetone, methanol) using capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration based on iodine consumption in a pyridine-free reagent system specific for water. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other toxic metals after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions using anion-exchange column and suppressed conductivity detector. |
| Sulfated Ash | Gravimetric Analysis | Residue mass after incineration at 700-800 C following sulfuric acid treatment, expressed as percentage of sample weight. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital apparatus per USP <741>. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light (589 nm) in solution, indicating chiral purity and enantiomeric excess. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium content after microwave-assisted digestion, using inductively coupled plasma optical emission spectrometry. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Direct measurement of hydrogen ion activity in saturated aqueous suspension using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering pattern analysis to determine D10, D50, D90 values. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 35–38°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.