Methyl (S)-(+)-3-hydroxybutyrate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 53562-86-0 |
| Product name | Methyl (S)-(+)-3-hydroxybutyrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl (S)-(+)-3-hydroxybutyrate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl (S)-(+)-3-hydroxybutyrate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl (S)-(+)-3-hydroxybutyrate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for drug synthesis | Used in asymmetric synthesis and chiral resolution |
| Organic Synthesis | Synthesis of chiral alcohols and esters | Applied in esterification, reduction, and condensation reactions |
| Biochemistry | Studying the β-hydroxybutyrate metabolic pathway | Employed in enzymatic transformation and metabolic labeling experiments |
| Materials Science | Chiral monomer precursor for polymers | Utilized in ring-opening polymerization and copolymerization reactions |
Manufacturing Quality Control of Methyl (S)-(+)-3-hydroxybutyrate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies (S)-3-hydroxybutyric acid methyl ester by retention time and peak area against a calibrated standard. |
| Optical Purity (Enantiomeric Excess) | Chiral Gas Chromatography (cGC) or Chiral HPLC | Separates enantiomers using a chiral stationary phase; ee calculated from peak area ratio of (S)- and (R)-enantiomers. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration based on iodine-sulfur dioxide reaction in pyridine/methanol medium. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Detects and quantifies volatile organic solvents (e.g., methanol, toluene) by equilibrium partitioning into headspace and GC-FID analysis. |
| Acid Value | Acid-Base Titration with NaOH | Determines free acid content by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Color | APHA Color Scale (Visual or Spectrophotometric) | Compares sample color to platinum-cobalt standard solutions; measured as APHA units at 455 nm absorbance. |
| Specific Rotation | [a]D Measurement using Polarimetry | Measures optical rotation of a solution at 20 C and 589 nm (Na D-line); confirms chiral integrity and concentration. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantifies total heavy metals after wet digestion by measuring absorbance of atomic vapor at element-specific wavelengths. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700–800 C) and weighing. |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Separates and quantifies chloride ions via conductivity detection (IC) or silver nitrate titration with endpoint detection. |
| Related Substances | Reverse-Phase High-Performance Liquid Chromatography (RP-HPLC) | Detects and quantifies structurally related impurities (e.g., diastereomers, hydrolysis products) using UV detection. |
| Density | Digital Density Meter (Oscillating U-tube) | Determines mass per unit volume at specified temperature (e.g., 20 C) by measuring resonant frequency shift of a vibrating U-tube filled with sample. |
Technical Specifications of Methyl (S)-(+)-3-hydroxybutyrate
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +21.0 to +24.0 deg (c=1, in CHCl3) |
| Refractive Index (n20/D) | 1.412 to 1.418 |
| Relative Density (20°C/25°C) | 0.995 to 1.005 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl (S)-(+)-3-hydroxybutyrate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl (S)-(+)-3-hydroxybutyrate
Safety Information of Methyl (S)-(+)-3-hydroxybutyrate
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of Methyl (S)-(+)-3-hydroxybutyrate
Industrial Methyl (S)-(+)-3-hydroxybutyrate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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