4-Chloro-2'-bromoacetophenone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 536-38-9 |
| Product name | 4-Chloro-2'-bromoacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Chloro-2'-bromoacetophenone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Chloro-2'-bromoacetophenone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Chloro-2'-bromoacetophenone
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediate | Used in the synthesis of antidepressant and antipsychotic drugs |
| Pesticides | Pesticide synthesis intermediate | Applied as an organic synthesis intermediate for preparing specific pesticide active ingredients |
| Chemical Research | Organic synthesis reagent | Used in laboratories for nucleophilic substitution and Friedel–Crafts acylation reactions |
| Chemicals | Dye and pigment synthesis | Serves as a key intermediate in dye synthesis processes |
| Materials Science | Functional material precursor | Applied in the synthesis of specialty polymers or optoelectronic materials |
Manufacturing Quality Control of 4-Chloro-2'-bromoacetophenone
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with UV detection (e.g., 254 nm), quantifying the main component via external standard method or area normalization. Suitable for rapid and accurate determination of target compound content in samples. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyzes chemical shifts, coupling splitting patterns of hydrogen (¹H-NMR) and carbon (¹³C-NMR) atoms to confirm whether the molecular structure matches the characteristic NMR spectrum of α-bromo-4-chloroacetophenone. |
| Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Utilizes capillary columns for separation of volatile components and mass spectrometry for qualitative and quantitative analysis, enabling identification and quantification of synthetic by-products or degradation impurities (e.g., unreacted starting materials, isomers). |
| Melting Point Determination | Capillary Melting Point Apparatus Method | Determines the melting temperature range according to pharmacopoeial standards (literature value approximately 78–80°C), used for preliminary assessment of purity and crystalline form consistency. |
| Moisture Content | Karl Fischer Titration Method | Measures trace moisture content using either volumetric or coulometric titration, ensuring product stability and preventing hydrolysis side reactions that may affect quality. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, quantifies heavy metals such as lead, cadmium, mercury, and arsenic, ensuring compliance with safety limits (e.g., ICH Q3D guidelines). |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Uses headspace injection technology to analyze volatile organic solvent residues (e.g., toluene, ethanol, dichloromethane), meeting ICH Q3C guidelines. |
| pH / Acidity-Alkalinity | pH Meter Method | Prepares a solution at a specified concentration or in an appropriate solvent system, then measures pH to evaluate acid-base stability and potential corrosiveness. |
| Appearance and Color | Visual Color Comparison Method | Observes solid color (should be white to off-white crystalline) and presence of foreign matter or discoloration under natural light or standard illumination, serving as an initial sensory criterion. |
| Content Uniformity (for formulations) | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Measures absorbance at maximum wavelength (e.g., ~245 nm) and calculates content using a calibration curve, suitable for rapid screening of batch samples. |
Technical Specifications of 4-Chloro-2'-bromoacetophenone
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.5% (GC-MS) |
| Melting Point | 62.0 - 66.0 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Chloro-2'-bromoacetophenone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Chloro-2'-bromoacetophenone
Packaging of 4-Chloro-2'-bromoacetophenone
Industrial 4-Chloro-2'-bromoacetophenone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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