ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 536759-91-8 |
| Product name | ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 536759-91-8
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 536759-91-8 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 536759-91-8
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as an intermediate in the synthesis of anticancer agents or kinase inhibitors | Employed in multistep organic synthesis involving functional group transformations to construct heterocyclic scaffolds or introduce targeted modifications |
| Medicinal Chemistry Research | Used for screening and optimizing biologically active pyrazolopyridine compounds | Applied in structure–activity relationship (SAR) studies for molecular modification and pharmacological evaluation |
| Chemical Reagents | Supplied as a high-purity organic building block for research purposes | Purified via column chromatography or recrystallization prior to use in small-scale laboratory synthesis |
Manufacturing Quality Control of 536759-91-8
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV with Gradient Elution | Separation and quantification of structurally related impurities (e.g., des-nitro, hydrolyzed ester, regioisomers) using gradient RP-HPLC and UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., ethyl acetate, methanol, toluene) based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Ni, As) after acid digestion, based on mass-to-charge ratio detection. |
| Residual Palladium | ICP-MS | Specific quantification of Pd catalyst residues post-hydrogenation, using isotope dilution or external calibration in digested sample solution. |
| Optical Rotation | [α]D Measurement | Determination of specific rotation using a polarimeter at 20 °C and sodium D-line (589 nm) to confirm chiral integrity (if applicable; compound is achiral but method included for batch consistency screening). |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on angular scattering intensity of laser light. |
| Melting Point | Automated Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, indicating crystallinity and purity. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing (700–800 °C) and weighing. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode to assess acidic/basic degradation products. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopoeial methods (if intended for pharmaceutical use). |
Technical Specifications of 536759-91-8
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–219 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 536759-91-8
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 536759-91-8
Packaging of 536759-91-8
Industrial 536759-91-8 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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