China Factory Direct
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| CAS number | 538-09-0 |
| Product name | Nortropine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of tropine | Tropine is synthesized via methylation of nortropine, followed by use in the production of alkaloids such as atropine and scopolamine |
| Pharmaceuticals | Preparation of tropane derivatives | Serves as a key chemical building block for synthesizing tropane alkaloids (e.g., anisodamine, anisodine) |
| Chemical Synthesis | Organic synthesis feedstock | Used to construct nitrogen-containing bicyclic structures in fine chemicals and pharmaceutical molecules |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase chromatography with UV detection at 210 nm based on peak area comparison to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient elution and UV detection, relative to main peak. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone) by gas chromatography with flame ionization detection against calibration standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol/pyridine medium. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation of chiral compound in solution using sodium D-line light to confirm stereochemical identity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Quantifies metals (Pb, Cd, Hg, As, etc.) after acid digestion by plasma emission spectroscopy with multi-element capability and low detection limits. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion in sulfuric acid medium, followed by high-temperature incineration and weighing. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines acidity/basicity of a defined aqueous suspension using calibrated glass electrode and pH meter. |
| Melting Point | Capillary Melting Point Apparatus | Identifies purity and identity by observing temperature range over which solid transitions to liquid under controlled heating. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of substance against defined standards (white to off-white crystalline powder, free from visible particles). |
| Loss on Drying | Thermogravimetric Analysis | Measures mass loss upon heating under controlled conditions (e.g., 105 C, 2 h) to determine volatile content including moisture and residual solvents. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 112-116°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -15.0° to -19.0° (c=1, in CHCl3) |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.