H-D-PRO-OBZL HCL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 53843-90-6 |
| Product name | H-D-PRO-OBZL HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for H-D-PRO-OBZL HCL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk H-D-PRO-OBZL HCL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of H-D-PRO-OBZL HCL
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral auxiliary and asymmetric synthesis intermediate for antiviral agents (e.g., HIV protease inhibitors) and anticancer drugs | Acts as a chiral auxiliary in asymmetric alkylation and allylation reactions; converted to D-proline or its derivatives via hydrolysis or hydrogenolytic deprotection |
| Organic Synthesis | Precursor to chiral catalyst ligands for constructing chiral pyrrolidine scaffolds | Coordinates with metals (e.g., Pd, Cu) to form chiral catalytic systems applied in C–N and C–O bond coupling reactions |
| Fine Chemicals | Key building block for synthesizing non-natural amino acid derivatives | Transformed into high-value functional molecules containing a pyrrolidine ring via multi-step processes including transesterification, amidation, and reduction |
Manufacturing Quality Control of H-D-PRO-OBZL HCL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies D-proline benzyl ester hydrochloride by reversed-phase HPLC with UV detection at 210 nm, using a calibrated standard. |
| Chiral Purity | Chiral HPLC | Measures enantiomeric excess by separation on a chiral stationary phase and UV detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration with iodine generated electrochemically in pyridine-methanol solvent. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., methanol, toluene) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Quantifies trace metals (Pb, Cd, Hg, As, Ni) after acid digestion by inductively coupled plasma optical emission spectrometry. |
| Chloride Content | Potentiometric Titration | Measures chloride ions using silver nitrate titrant and silver/silver chloride indicator electrode. |
| pH of Aqueous Solution | pH Meter | Determines pH of a 1% w/v aqueous solution using calibrated glass electrode pH meter. |
| Appearance | Visual Inspection | Evaluates physical state, color, and clarity against standard reference under controlled white light. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary method per USP <741>. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic residue after high-temperature ashing (500–600 C) and weighing. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., free D-proline, benzyl alcohol, diastereomers) using gradient HPLC. |
| Microbial Contamination | Membrane Filtration | Assesses absence of aerobic microorganisms per pharmacopeial limits using filtration and culture on soybean-casein digest agar. |
Technical Specifications of H-D-PRO-OBZL HCL
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +42.0 to +46.0 deg (c=1, H2O) |
| Melting Point | 158 to 162 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of H-D-PRO-OBZL HCL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of H-D-PRO-OBZL HCL
Packaging of H-D-PRO-OBZL HCL
Industrial H-D-PRO-OBZL HCL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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