China Factory Direct
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| CAS number | 53956-04-0 |
| Product name | Glycyrrhizic acid ammonium salt |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Cosmetics | Anti-inflammatory, anti-allergic, skin-soothing | Incorporated into emulsions, creams, and serums as an active ingredient to alleviate sensitive skin conditions |
| Pharmaceuticals | Treatment of liver disease, detoxification, anti-inflammatory action | Formulated into compound glycyrrhizin preparations for oral or injectable administration to modulate immune response and inhibit hepatic injury |
| Food | Sweetener, flavor enhancer | Used as a natural sweetening component in sugar-free or functional foods, providing concurrent antioxidant activity |
| Oral Care | Inhibition of oral inflammation, anti-ulcer | Incorporated into toothpaste and mouthwash to relieve gingival bleeding and oral mucosal damage |
| Tobacco | Improvement of smoke taste, reduction of irritation | Added as a tobacco additive in cigarettes or heated tobacco products to enhance inhalation comfort |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Thin Layer Chromatography (TLC) | Identification is performed by comparing the Rf values of test sample spots with those of reference standards after development and visualization. |
| Assay | High Performance Liquid Chromatography (HPLC) | A reversed-phase C18 column with a UV detector (typically at 250–254 nm) is used, with a mobile phase consisting of methanol-water-phosphoric acid; quantification is performed using the external standard method to determine the content of ammonium glycyrrhizinate. |
| Impurity Check (Related Substances) | High Performance Liquid Chromatography (HPLC) | HPLC is employed to detect structural analogs or degradation products potentially present in ammonium glycyrrhizinate; impurity limits are determined based on peak areas. |
| Water Content | Karl Fischer Titration | Utilizes electrochemical titration to precisely determine water content in samples, suitable for trace moisture analysis. |
| Drying Loss | Thermogravimetric Analysis (Oven Method) | The sample is dried at a specified temperature (e.g., 105°C) until constant weight is achieved; drying loss is calculated based on weight reduction to control moisture and volatile components. |
| Residue on Ignition | Residue on Ignition Method | The weight of inorganic residues remaining after high-temperature incineration of the sample is measured to control inorganic impurity levels. |
| Heavy Metals | Thioacetamide Method (Pharmacopoeia Method) | Under weakly acidic conditions, heavy metal ions react with thioacetamide to form colored sulfides; limits are determined by colorimetric comparison. |
| Microbial Limits | Microbial Limit Test | Performed in accordance with the Chinese Pharmacopoeia to determine total aerobic microbial count, mold and yeast counts, and to detect specified control microorganisms (e.g., Escherichia coli). |
| Content Uniformity | HPLC or Ultraviolet Spectrophotometry (UV) | For dosage forms, this test determines whether the content of ammonium glycyrrhizinate in each unit dose meets uniformity requirements. |
| pH | pH Measurement Method | The sample is dissolved in water or an appropriate solvent, and the pH of the solution is measured using a pH meter to control product stability. |
| Test Item | Specification |
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| Appearance | White to light yellow powder or crystals |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.5% |
| Optical Rotation | +48±4° (c=1, in H2O) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.