China Factory Direct
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| CAS number | 5399-03-1 |
| Product name | 2-Iodo-4-nitroanisole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antitumor agents (e.g., benzimidazole derivatives) | Multi-step reaction involving nitration, iodination, and methylation; or prepared via diazotization and iodination of 2-amino-4-nitroanisole |
| Pesticide Development | Building block for novel insecticidal and fungicidal molecules containing iodinated heterocyclic structures | Used as an aryl substitution module in Suzuki or Heck coupling reactions to introduce nitro and iodo functional groups, thereby modulating biological activity and metabolic stability |
| Organic Synthesis | Multifunctional building block for constructing asymmetric catalyst ligands and functional material monomers | Selective utilization of the C–I bond in palladium-catalyzed cross-coupling reactions (e.g., Stille, Sonogashira); the nitro group may be subsequently reduced to an amino group for further derivatization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., isomers, nitro-reduction products) via gradient HPLC with UV detection and relative response factor correction. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., methanol, toluene) using headspace GC with flame ionization detection. |
| Moisture Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Measures trace metal contaminants (e.g., Pb, Cd, Ni) after acid digestion by optical emission spectroscopy of atomized plasma. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on anion-exchange column. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after combustion with sulfuric acid treatment and high-temperature incineration, followed by weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against standard specifications under controlled lighting. |
| Loss on Drying | Thermogravimetric Analysis | Measures weight loss upon heating under specified conditions to determine volatile content excluding water. |
| pH of Aqueous Suspension | pH Meter | Evaluates acidity/basicity of a defined suspension in water using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in dispersion medium by analyzing angular scattering pattern of laser beam. |
| Test Item | Specification |
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| Appearance | Brown solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 78–82°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.