Z-PHG-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 53990-33-3 |
| Product name | Z-PHG-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Z-PHG-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Z-PHG-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Z-PHG-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for synthesizing β-lactam antibiotics (e.g., cephalosporins and penicillin derivatives) | Participates in asymmetric synthesis, condensation reactions, or enzymatic resolution—via Cbz (benzyloxycarbonyl)-protected L-phenylglycine—to construct the chiral side chain of antibiotic molecules |
| Pharmaceuticals | Chiral building block for synthesizing antiviral and peptide-based drugs | Serves as a source of specific chiral amino acid residues in solid-phase or solution-phase peptide synthesis; undergoes deprotection prior to peptide bond formation |
| Chemical Research | Chiral auxiliary or chiral source for asymmetric synthesis studies | Leverages its stable chiral center to direct stereoselective construction of new compounds, commonly applied in organic synthetic methodology development |
Manufacturing Quality Control of Z-PHG-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination using a chiral stationary phase and UV detection, resolving L- and D-enantiomers. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Mass loss measured after drying under controlled temperature and time to determine volatile content including residual solvents and moisture. |
| Residual Solvents | GC-FID | Identification and quantification of common organic solvents (e.g., ethyl acetate, methanol) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on atomic emission intensity. |
| Chloride Content | Potentiometric Titration with AgNO3 | Determination of chloride ions by titration with silver nitrate using a silver indicator electrode and endpoint detection via potential change. |
| Sulfated Ash | Gravimetric (550 C, 2 h) | Residue mass after high-temperature incineration to assess inorganic impurities, expressed as percentage of sample weight. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light to confirm chiral integrity and concentration, reported as [alpha]D value. |
| pH of 1% Aqueous Solution | pH Meter | Direct potentiometric measurement of hydrogen ion activity in a standardized aqueous suspension. |
| Related Substances | HPLC-UV | Detection and quantification of structurally similar impurities (e.g., Cbz-glycine, benzyl alcohol, L-phenylglycine) using gradient HPLC. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric determination of water based on stoichiometric reaction with iodine in pyridine-methanol medium. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial guidelines. |
Technical Specifications of Z-PHG-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148.0 to 152.0 °C |
| Optical Rotation | +114.0 to +118.0 ° (c=1, in 1M HCl) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Z-PHG-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Z-PHG-OH
Packaging of Z-PHG-OH
Industrial Z-PHG-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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