China Factory Direct
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| CAS number | 54-12-6 |
| Product name | DL-Tryptophan |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Food Industry | Nutritional fortificant for supplementation of essential amino acids | Added to infant formula, dietary supplements, and functional foods |
| Feed Industry | Feed additive to promote animal growth and improve feed conversion efficiency | Incorporated into livestock, poultry, and aquaculture feeds as an amino acid balancing component |
| Pharmaceutical Industry | Synthetic drug intermediate for antidepressants, sedatives, and related compounds | Used in chemical synthesis or biotransformation processes, such as production of serotonin-related pharmaceuticals |
| Cosmetics Industry | Skin-care ingredient with antioxidant and soothing properties | Formulated into skin-care products via compounding processes to produce emulsions, serums, and similar dosage forms |
| Biotechnology | Component of microbial culture media for fermentation-based production of other metabolites | Supplied as a nitrogen source in fermentation media to support growth and metabolite synthesis of specific microbial strains |
| Test Item | Common Testing Method | Method Overview |
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| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase column (e.g., C18) and a UV detector (typically around 280 nm). Identification is based on retention time, and quantification is achieved by peak area. Accurately determines the content of DL-Tryptophan. Commonly employs a buffered mobile phase (e.g., phosphate buffer) with an organic solvent (e.g., methanol or acetonitrile) under gradient or isocratic elution. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Same as above; calculates total purity based on the relative areas of the main peak and impurity peaks, assessing the level of organic impurities. |
| Specific Optical Rotation | Polarimetry | Measures the specific optical rotation of the sample using an automatic polarimeter at a specified wavelength (usually sodium D-line, 589 nm), used to detect deviations in optical isomer composition (DL-form should be close to racemic, with theoretical specific rotation near 0°). |
| Water Content | Karl Fischer Titration | Determines water content precisely based on the reaction of iodine and sulfur dioxide with water in an anhydrous environment. Suitable for trace moisture detection. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar to assay method, but with optimized separation conditions to detect potential impurities such as synthesis intermediates, degradation products, or other amino acid-related impurities. Typically reports individual impurity peaks and total impurity levels. |
| Melting Point | Melting Point Determination | Determines the melting temperature of DL-Tryptophan using a melting point apparatus or capillary method, used for identification and preliminary purity assessment (pure material melts at approximately 289–291°C with decomposition). |
| Solution Clarity and Color | Visual Comparison or Spectrophotometry | The sample is prepared into a solution of specified concentration, and its clarity and color are observed and compared against standard turbidity or color solutions, indicating the presence of insoluble particles or colored impurities. |
| Loss on Drying | Thermogravimetric Method (or Oven Method) | The sample is dried at a specified temperature (e.g., 105°C) until constant weight. The weight loss is used to calculate the content of volatile components (mainly water and minor solvents). |
| Sulfated Ash (Residue on Ignition) | Residue on Ignition Test | Measures the mass of inorganic residue remaining after high-temperature incineration of the sample, used to determine inorganic impurity content. Usually measured after sulfuric acid treatment and weighing. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determines the content of heavy metal elements such as lead, cadmium, mercury, and arsenic using atomic absorption spectroscopy or inductively coupled plasma mass spectrometry (ICP-MS), ensuring compliance with pharmacopoeial or food safety standards. |
| Microbial Limits | Microbial Limit Test | Includes tests for total aerobic microbial count, mold and yeast count, and specified microorganisms (e.g., *Escherichia coli*, *Salmonella*), performed according to cultivation and identification procedures outlined in the *Chinese Pharmacopoeia* or relevant food/pharmaceutical standards. |
| Test Item | Specification |
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| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 286-289°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -0.5° to +0.5° (c=1, H2O) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.