China Factory Direct
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| CAS number | 5405-40-3 |
| Product name | L-PANTOLACTONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of pantothenic acid (vitamin B5) | Condensation of S-pantolactone with β-alanine via enzymatic or chemical methods to produce pantothenic acid |
| Biotechnology | Chiral building block for the preparation of antibiotics and metabolites | Serves as a precursor in biocatalytic reactions, enabling stereoselective reduction or acylation to construct complex molecular frameworks |
| Food Additives | Precursor to vitamin B5 for use in nutritional fortification | Hydrolyzed and purified to yield pantothenic acid, which is incorporated into dietary supplements or functional foods |
| Cosmetics | Precursor to active ingredients in moisturizing and skin-repair formulations | Chemically converted to panthenol (pantothenyl alcohol) for use as an active ingredient in skincare products |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Pantothenol Lactone Content) | HPLC with UV detection | Quantification based on retention time and peak area comparison against a certified reference standard using a reversed-phase C18 column and UV detection at 210 nm. |
| Related Substances | HPLC with UV detection | Separation and quantification of impurities (e.g., panthenol, pantoic acid, hydrolysis products) relative to the main peak using gradient elution and UV detection. |
| Water Content | Karl Fischer titration | Electrochemical titration with iodine reagent where water reacts stoichiometrically with iodine, sulfur dioxide, and base in methanol medium. |
| Residue on Ignition | Gravimetric analysis | Heating sample to 700-800 C to volatilize organic matter, then weighing inorganic residue as sulfate ash. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element detection via plasma excitation and emission spectroscopy; quantification based on characteristic atomic emission lines. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on an anion-exchange column with conductivity detection, calibrated against NaCl standards. |
| Sulfate Impurity | Ion Chromatography | Anion-exchange separation followed by suppressed conductivity detection; quantified using sodium sulfate calibration. |
| Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating enantiomeric purity and identity. |
| Melting Point | Capillary melting point apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary tube method per USP <741>. |
| pH of Aqueous Solution | pH meter | Potentiometric measurement of hydrogen ion activity in a saturated aqueous suspension or 1% w/v solution. |
| Loss on Drying | Thermogravimetric analysis | Weight loss measured after drying at 105 C for 2 hours under vacuum or air, reflecting volatile content including residual solvents. |
| Residual Solvents (e.g., Ethanol, Acetone) | Gas Chromatography with FID | Separation by volatility on a capillary column, detection by flame ionization, quantified against internal/external standards. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=99.0% (GC-MS) |
| Melting Point | 48.0–52.0 °C |
| Optical Rotation | +48.0 to +52.0 ° (c=1, in methanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.3% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.