China Factory Direct
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| CAS number | 54054-85-2 |
| Product name | 1-(3-Nitrophenyl)piperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate synthesis | Used in the synthesis of biologically active drug molecules—such as antipsychotics and antidepressants—as a key intermediate containing the piperazine moiety |
| Organic synthesis | Chemical reagent | Employed as a building block in laboratory-scale synthesis of complex organic molecules; participates in coupling and reduction reactions to introduce the nitrophenylpiperazine structure |
| Agrochemical R&D | Agrochemical intermediate | Used in the synthesis of novel pesticide active ingredients, serving as a nitrogen-containing heterocyclic precursor in multistep synthetic processes |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separates and quantifies impurities (e.g., residual aniline, nitroaniline isomers, piperazine derivatives) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., toluene, DMF, methanol) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Determines trace water via electrochemical iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Quantifies elemental impurities at sub-ppb levels using inductively coupled plasma mass spectrometry after acid digestion and matrix-matched calibration. |
| Chloride Ion | Ion Chromatography (IC) with Conductivity Detection | Separates and detects chloride anions using anion-exchange column and suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Appearance and Color | Visual Inspection & Hazen/APHA Color Scale | Assesses physical state (crystalline powder), color (against platinum-cobalt standard), and absence of visible particulates or discoloration. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determines inorganic ash content by high-temperature incineration (500–600 °C) and weighing residual non-volatile matter. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral purity (if applicable; compound is achiral, but method verifies absence of optically active contaminants). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 78.0–82.0°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.