2-Hydroxy-5-nitropyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5418-51-9 |
| Product name | 2-Hydroxy-5-nitropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Hydroxy-5-nitropyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Hydroxy-5-nitropyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Hydroxy-5-nitropyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antimicrobial, antitumor, or neurosystem-related compounds | Introduced into the target molecular scaffold via nucleophilic substitution, reduction, or coupling reactions |
| Pesticides | Used to synthesize pyridine-containing insecticidal or herbicidal active ingredients | Participates in heterocycle construction following nitro group reduction and hydroxyl group protection/activation |
| Organic Synthesis | Used as a versatile synthetic building block for constructing complex nitrogen-containing heterocycles | Enables regioselective functionalization leveraging the electron-withdrawing effect of the nitro group and the coordinating ability of the hydroxyl group |
| Materials Science | Used as a ligand precursor for preparing functional metal-complex materials | Coordinates with transition metals (e.g., copper, zinc) to form luminescent or catalytic materials |
Manufacturing Quality Control of 2-Hydroxy-5-nitropyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~260 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., unreacted 2-aminopyridine, nitration by-products) using gradient HPLC-UV; identification via retention time matching and threshold-based reporting. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine reagent to determine water content based on stoichiometric reaction with iodine and sulfur dioxide in pyridine-methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight; residue mass expressed as percentage of original sample, indicating inorganic ash content. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion; detection based on element-specific atomic emission intensities in high-temperature plasma. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on anion-exchange column with suppressed conductivity detection; quantified against chloride standard calibration curve. |
| Sulfate Impurity | Turbidimetric Analysis | Reaction with barium chloride under acidic conditions to form barium sulfate precipitate; turbidity measured spectrophotometrically at 420 nm. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range over which solid-to-liquid phase change occurs. |
| Organic Volatile Impurities | GC-FID | Headspace or direct injection GC analysis with flame ionization detection to identify and quantify residual solvents (e.g., methanol, DMF, acetonitrile). |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting and white background. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode; indicates acidic/basic degradation products. |
| Bulk Density | Tap Density Tester | Determined by measuring mass per unit volume after standardized tapping; used for processability and formulation consistency assessment. |
Technical Specifications of 2-Hydroxy-5-nitropyridine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Hydroxy-5-nitropyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Hydroxy-5-nitropyridine
Packaging of 2-Hydroxy-5-nitropyridine
Industrial 2-Hydroxy-5-nitropyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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