3-Fluoro-2-nitropyridine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 54231-35-5 |
| Product name | 3-Fluoro-2-nitropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 3-Fluoro-2-nitropyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Fluoro-2-nitropyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Fluoro-2-nitropyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of fluorinated aromatic rings in drug molecules | Fluorination, nitration |
| Agrochemical Intermediates | Preparation of insecticidal compounds | Fluorination, nitration |
| Materials Science | Production of fluorinated polymers or materials | Fluorination, polymerization |
Manufacturing Quality Control of 3-Fluoro-2-nitropyridine
| Test Item | Common Testing Methods | Method Summary |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection + Physical Property Measurement | Observe the sample's color and physical state (usually yellow to orange crystalline or powder), measure melting point range (literature value approximately 58–62 °C), and ensure it conforms to pharmacopoeia or internal quality control standards. |
| Content Determination (Main Component) | High-Performance Liquid Chromatography (HPLC) | Use a C18 chromatographic column, with methanol/water or acetonitrile/water (with a small amount of acid such as formic acid) as the mobile phase, and a UV detector (254–280 nm) for detection. Quantification is performed using external standard method, ensuring main component purity ≥98.0%. |
| Impurity Profile Analysis | HPLC (Gradient Elution) | Use a gradient elution program to separate possible impurities (such as unreacted raw materials, dinitro byproducts, hydrolysis products, and fluorinated isomers). Control single impurity and total impurity levels (e.g., ≤0.5%) via peak area normalization or reference substance method. |
| Residual Solvents | Gas Chromatography (GC) | Use DB-624 or HP-INNOWAX chromatographic columns, with FID detector, and headspace or direct injection. Detect common organic solvent residues such as ethanol, acetone, acetonitrile, and DMF according to ICH Q3C standards. |
| Moisture Content Determination | Karl Fischer Titration | Determine trace moisture content using coulometric or volumetric methods. Control moisture content ≤0.5% (may be relaxed to 1.0% depending on usage) to avoid hydrolysis or stability issues. |
| Fluorine Content Verification | Ion Chromatography (IC) or Fluoride Ion-Selective Electrode | After sample alkaline fusion or hydrolysis, determine F⁻ ion concentration using ion chromatography or fluoride ion-selective electrode. Verify that fluorine atoms conform to theoretical content (theoretical F% ≈ 10.1%). |
| Nitro Group Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirm the presence of nitro groups through characteristic absorption peaks (e.g., asymmetric and symmetric stretching vibrations at ~1530 cm⁻¹ and ~1350 cm⁻¹), excluding interference from other nitrogen-containing functional groups. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (¹H NMR & ¹³C NMR) | Measure in DMSO-d₆ or CDCl₃. Confirm the position of fluorine atoms (~δ 7.0–7.5 ppm) and nitro group effects on the pyridine ring via chemical shifts and splitting patterns, verifying molecular structure. |
| Heavy Metal Residues | Atomic Absorption Spectrometry (AAS) or ICP-MS | Determine lead, cadmium, mercury, arsenic, copper, etc., after sample digestion. Ensure compliance with ICH Q3D or pharmacopoeia limits (e.g., Pb ≤5 ppm). |
| Solubility and pH (in Solution) | Solubility Test + pH Meter Measurement | Determine solubility in water, ethanol, DMSO, etc. Measure pH of saturated solution (typically neutral to slightly acidic) for compatibility evaluation in formulations. |
Technical Specifications of 3-Fluoro-2-nitropyridine
| Test Item | Specification |
|---|---|
| Appearance | Light yellow to orange crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65–69°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 3-Fluoro-2-nitropyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Fluoro-2-nitropyridine
Packaging of 3-Fluoro-2-nitropyridine
Industrial 3-Fluoro-2-nitropyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply