China Factory Direct
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| CAS number | 5438-36-8 |
| Product name | 5-Iodovanillin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Intermediate in the synthesis of thyroid hormone analogs and antitumor agents | Iodination; recrystallization for purification |
| Fine Fragrance Industry | Fixative and synthetic precursor for vanillin derivatives | Modification reactions including esterification and oxidation |
| Organic Synthesis | Substrate for coupling reactions to construct iodinated aromatic heterocycles | Palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) |
| Materials Science | Functional unit in charge-transport layers of organic optoelectronic materials | Halogenation (bromination/iodination) of aromatic rings; polymerization |
| Test Item | Common Testing Method | Method Description |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and state of the sample under natural light or standard light sources to determine if it is a white to off-white crystalline powder. |
| Identification | Infrared Spectroscopy (IR) | Scan the sample and reference standard in the range of 4000–400 cm⁻¹ using infrared spectroscopy, compare characteristic absorption peaks (such as hydroxyl, carbonyl, C-I bonds) to confirm structural consistency. |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR) | Dissolve the sample in deuterated solvent and obtain hydrogen NMR spectrum. Compare chemical shifts for aromatic rings, methoxy groups, aldehyde groups, and iodine substitution positions to confirm molecular structure. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with methanol-water or acetonitrile-water as the mobile phase. Detect using a UV detector (e.g., at 280 nm). Quantify the main component content by external standard or internal standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Optimize the gradient elution program based on content determination to separate and detect possible synthetic intermediates, degradation products, and other organic impurities. Usually, total impurity should be ≤ 0.5%. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Method | Dry the sample at 105°C until constant weight is achieved. Calculate the percentage of weight loss; generally requires ≤ 0.5%. |
| Residue on Ignition | Sulfate Ash Method | Treat the residue after high-temperature ignition with sulfuric acid, weigh the residue, and calculate the residue content. Typically requires ≤ 0.1%. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and measure the content of heavy metals such as lead, cadmium, mercury, and arsenic. Comply with pharmacopoeia or customer-specified limits (e.g., ≤ 10 ppm). |
| Moisture | Karl Fischer Titration (KFT) | Accurately measure the moisture content of the sample using a Karl Fischer titrator, suitable for trace moisture detection. Generally requires ≤ 0.5%. |
| Melting Point | Capillary Melting Point Determination | Determine the initial and final melting temperatures using a melting point apparatus. The typical melting point range for 5-iodovanillin is approximately 150–154°C, used for preliminary identification and purity assessment. |
| Test Item | Specification |
|---|---|
| Appearance | White to orange crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 126–129°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.