China Factory Direct
|
|
| CAS number | 544-31-0 |
| Product name | Palmitoylethanolamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeMaterial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Cosmetics | Emulsifier, thickener | Formulation mixing, heat dissolution |
| Lubricants | Additive | Uniform dispersion, blending |
| Plastics | Antistatic agent | Melt compounding |
| Detergents | Foam stabilizer | Chemical synthesis, formulation |
| Textiles | Softener | Impregnation, drying |
| Pharmaceuticals | Excipient (stabilizer) | Powder blending, granulation |
| Test Item | Common Test Methods | Method Summary |
|---|---|---|
| Appearance and Physical Form | Visual inspection, Melting point determination | Observe sample color and state (typically white to off-white crystalline powder); determine melting range (PEA melts at approximately 80–85°C) to assess purity and crystallinity. |
| Assay (Content Determination) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with a mobile phase of methanol-water or acetonitrile-water under gradient elution; detect with UV detector at 210–220 nm; quantify active ingredient using external standard method. This method is accurate and highly specific. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Apply gradient elution to detect potential synthesis-related impurities (e.g., free palmitic acid, ethanolamine, dimers); set acceptance criteria (e.g., ≤0.5%) in compliance with ICH Q3B guidelines. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection with FID detector to measure residual solvents (e.g., ethanol, ethyl acetate, dichloromethane); comply with ICH Q3C standards. |
| Water Content | Karl Fischer Titration (KF) | Determine trace moisture using coulometric or volumetric method; control water content (typically ≤0.5%) to prevent hydrolysis or microbial growth. |
| Residue on Ignition (Ash Content) | Loss on Ignition Test | Ignite sample at 500–600°C to constant weight to determine inorganic residue; evaluate level of inorganic impurities (generally required ≤0.1%). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measure heavy metal content (e.g., Pb, Cd, Hg, As); meet pharmacopeial limits (e.g., USP/EP requirements such as Pb ≤5 ppm). |
| Particle Size Distribution (if applicable) | Laser Particle Size Analyzer | For powder formulations, measure particle size distribution (D50) to ensure proper flowability and solubility for formulation requirements. |
| Infrared Spectrum (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare with reference spectrum to confirm structural consistency of functional groups (e.g., amide I band at 1650 cm⁻¹, amide II band at 1550 cm⁻¹, C-O stretching), used for identification. |
| Solubility | Shake Flask Method / Visual Observation | Determine solubility behavior in various solvents (water, ethanol, diethyl ether, vegetable oil); confirm lipophilic characteristics (slightly soluble in water, readily soluble in ethanol and oils), supporting formulation development. |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.5% (GC-MS) |
| Melting Point | 102–106°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.