4-Nitro-2-picoline N-oxide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5470-66-6 |
| Product name | 4-Nitro-2-picoline N-oxide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Nitro-2-picoline N-oxide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Nitro-2-picoline N-oxide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Nitro-2-picoline N-oxide
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of 2-methyl-4-aminopyridine N-oxide (a key pharmaceutical intermediate) | Reduction (typically using iron powder/hydrochloric acid or catalytic hydrogenation to convert nitro to amino group) |
| Chemicals | Raw material for synthesis of pyridine derivatives | Functional group transformation (e.g., oxidation, nucleophilic substitution) |
| Organic Synthesis | Organic synthesis and chemical reagent | Laboratory-scale synthesis |
Manufacturing Quality Control of 4-Nitro-2-picoline N-oxide
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode-array detection; peak area comparison relative to main peak. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection for quantification of common solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric titration with iodine-based reagent; measures water via stoichiometric reaction with sulfur dioxide and pyridine in methanol medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal analysis after acid digestion; detects Pb, Cd, Hg, As, Cr at sub-ppb levels per ICH Q3D. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anion on anion-exchange column with suppressed conductivity detection; quantified against NaCl standard. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by sulfuric acid treatment and final weighing of residual inorganic ash. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range at which solid transforms to liquid. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standard. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Weight loss measured upon heating to 105 C under nitrogen; reflects volatile content including residual moisture and low-boiling impurities. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode; indicates acidic/basic impurity profile. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values per ISO 13320. |
Technical Specifications of 4-Nitro-2-picoline N-oxide
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–127 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Nitro-2-picoline N-oxide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Nitro-2-picoline N-oxide
Packaging of 4-Nitro-2-picoline N-oxide
Industrial 4-Nitro-2-picoline N-oxide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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