METHYL 4-IODO-3-METHYLBENZOATE Bulk Supply for Industrial Use

China Factory Direct
CAS number 5471-81-8
Product name METHYL 4-IODO-3-METHYLBENZOATE
Stock Stock readily available; annual supply capacity exceeding 1,000 tons.
Grade Material GradeSpecialty GradeIndustrial Grade
Packaging 25KG/bag500KG/bag1000KG/bag
Sample Test Samples Available (Click to Request Samples)
COA View COA
Price Get Quote
Supply Type Bulk / Contract manufacturing / OEM
Shipping FCL / LCL available
Payment Terms Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C).
Manufacturer Greenrock Chemical(China Factory)
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CIF (Cost, Insurance, Freight)
EXW (Ex Works)

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Documents We Provide for METHYL 4-IODO-3-METHYLBENZOATE

COA TDS SDS NMR MOA Certificate of Origin Transport Report TSCA Declaration Production Flow Chart
Pre-sale: Only COA, SDS and NMR are available.
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk METHYL 4-IODO-3-METHYLBENZOATE Supplier from China

17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.

Industrial Applications of METHYL 4-IODO-3-METHYLBENZOATE

Industry Application Process
Pharmaceutical Intermediates Key intermediate for synthesizing anticancer agents (e.g., EGFR inhibitors) Constructing the aromatic ring scaffold via Suzuki or Heck coupling, followed by hydrolysis and amidation to prepare the active pharmaceutical ingredient
Organic Synthesis Used to prepare polysubstituted iodoarenes and functionalized benzoic acid derivatives Introducing additional functional groups via transition-metal-catalyzed (e.g., Pd-, Cu-mediated) cross-coupling reactions or selective lithiation–electrophilic trapping reactions
Materials Science Structural building block for liquid crystal molecules or organic optoelectronic materials Building conjugated π-systems or rigid mesogenic units through ester group transformations (e.g., aminolysis, reduction) or iodine atom–involved polymerization reactions

Manufacturing Quality Control of METHYL 4-IODO-3-METHYLBENZOATE

Detection Item Common Analytical Method Method Overview
Assay (Purity) HPLC-UV Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard.
Related Substances (Impurities) HPLC-UV or UPLC-MS Separation and detection of structurally related impurities (e.g., isomers, deiodinated, hydrolyzed, or oxidized by-products) using gradient elution and UV or mass-selective detection.
Residual Solvents GC-FID Headspace gas chromatography with flame ionization detection to quantify residual methanol, dichloromethane, or toluene based on calibrated external standards.
Heavy Metals (Pb, Cd, Hg, As) ICP-MS Multi-element quantification of trace heavy metals after acid digestion, leveraging high sensitivity and isotopic resolution of inductively coupled plasma mass spectrometry.
Water Content Karl Fischer Titration (Coulometric) Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample water in anhydrous methanol-based reagent.
Acid Value Acid-Base Titration (NaOH in methanol) Neutralization of free carboxylic acid groups (if present due to ester hydrolysis) with standardized sodium hydroxide solution using phenolphthalein or potentiometric endpoint detection.
Iodine Content Oxidative Combustion IC High-temperature combustion followed by ion chromatographic separation and conductivity detection of iodide ions to verify stoichiometric iodine incorporation.
Melting Point Capillary Melting Point Apparatus Thermal transition measurement via controlled heating of crystalline sample; used for identity confirmation and assessment of crystallinity/purity.
Appearance & Color Visual Inspection / Hazen/APHA Color Scale Subjective visual evaluation against water-white standard or quantitative colorimetric comparison using platinum-cobalt scale.
Residue on Ignition Gravimetric Analysis Weighing of non-volatile inorganic residue remaining after high-temperature ashing at 700–800 °C.
Chloride Impurity Ion Chromatography (IC) with Conductivity Detection Separation and quantification of chloride ions (from synthesis reagents or side reactions) using anion-exchange column and suppressed conductivity detection.
Optical Rotation Polarimetry Measurement of specific rotation using sodium D-line light to confirm absence of chiral contaminants (though compound is achiral, detects enantiomeric impurities from asymmetric synthesis steps).

Technical Specifications of METHYL 4-IODO-3-METHYLBENZOATE

Test Item Specification
Appearance Pale-yellow solid
Purity >=98.5% (GC-MS)
Total Impurities <=1.5%
Single Impurity <=0.5%
Water Content (KF) <=0.5%
Melting Point 72–76°C
Identification (NMR) Consistent with structure
Identification (IR) Consistent with structure
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com

Download COA of METHYL 4-IODO-3-METHYLBENZOATE

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NMR Spectra of METHYL 4-IODO-3-METHYLBENZOATE

Safety Information of METHYL 4-IODO-3-METHYLBENZOATE

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Signal Word Danger
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Packaging of METHYL 4-IODO-3-METHYLBENZOATE

We have a diverse range of chemicals in stock. Available in Bagged goods (25 kg.),Big bags (500 kg.), Big bags (1000 kg.).

Industrial METHYL 4-IODO-3-METHYLBENZOATE Procurement FAQ

1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.

2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.

3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.

4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.

5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.

6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.

7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.

8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.

9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.

Industrial
Use
Bulk
Supply
Factory
Direct
ISO 9001
Certified
Samples
Available
Stable
Supply