5-BROMO-2-METHOXY-NICOTINIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 54916-66-4 |
| Product name | 5-BROMO-2-METHOXY-NICOTINIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-BROMO-2-METHOXY-NICOTINIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-BROMO-2-METHOXY-NICOTINIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-BROMO-2-METHOXY-NICOTINIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of anticancer agents (e.g., EGFR inhibitors) | Undergoes amidation with amines, or multi-step transformations—including decarboxylation and halogen substitution—to construct the active molecular core |
| Pesticide R&D | Structural modification for novel neonicotinoid insecticides | Bromine atom participates in Suzuki or Heck coupling to introduce heterocyclic groups, optimizing insecticidal activity |
| Organic Synthesis | Multifunctional building block for constructing nitrogen-containing heterocycles | Undergoes cross-coupling reactions under palladium catalysis, or methoxy deprotection/bromine substitution to prepare downstream derivatives |
Manufacturing Quality Control of 5-BROMO-2-METHOXY-NICOTINIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities by gradient HPLC-UV; identification and quantification against reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water. |
| Heavy Metals | ICP-OES | Digestion followed by multi-element quantification via inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with conductivity detection; quantified using chloride standard calibration. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C to oxidize organic matter, followed by weighing of residual inorganic sulfates. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity against established reference samples under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measurement of scattered laser light intensity as a function of angle to derive volume-based particle size distribution. |
| Optical Rotation | Polarimetry | Determination of specific rotation using sodium D-line light passing through a solution in a temperature-controlled cell. |
| Residual Palladium | ICP-MS | Microwave-assisted digestion followed by ultra-trace quantification using inductively coupled plasma mass spectrometry. |
Technical Specifications of 5-BROMO-2-METHOXY-NICOTINIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 148–152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-BROMO-2-METHOXY-NICOTINIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-BROMO-2-METHOXY-NICOTINIC ACID
Safety Information of 5-BROMO-2-METHOXY-NICOTINIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-BROMO-2-METHOXY-NICOTINIC ACID
Industrial 5-BROMO-2-METHOXY-NICOTINIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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