Pyridine, 2-chloro-5-iodo-4-methyl- Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 550347-54-1 |
| Product name | Pyridine, 2-chloro-5-iodo-4-methyl- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Pyridine, 2-chloro-5-iodo-4-methyl-
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Pyridine, 2-chloro-5-iodo-4-methyl- Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Pyridine, 2-chloro-5-iodo-4-methyl-
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing kinase inhibitor–based anticancer drugs (e.g., BTK inhibitors) | Used to construct the pyridine ring side chain via Suzuki coupling or Buchwald–Hartwig amination |
| Agrochemicals | Structural building block for novel insecticides and fungicides, enabling optimization of biological activity and metabolic stability | Employed as a heterocyclic building block in multistep syntheses; the iodine atom facilitates subsequent halogen exchange or metalation reactions |
| Materials Science | Synthetic precursor for electron-transport layer materials in organic light-emitting diode (OLED) devices | Subjected to lithium–halogen exchange followed by reaction with aldehydes or ketones to generate functionalized pyridine derivatives, or used to prepare iodinated ligands for metal complexes |
Manufacturing Quality Control of Pyridine, 2-chloro-5-iodo-4-methyl-
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification by retention time matching with reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone, toluene) using gas chromatography with flame ionization detection and external calibration. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generated electrochemically in pyridine-methanol medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Iodine Content | Potentiometric Titration with Sodium Thiosulfate | Determines total iodine after oxidative digestion to iodate, followed by reduction to iodine and back-titration with thiosulfate. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against established visual standards. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after drying at 105 C for 2 hours under vacuum. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry dispersion mode using Mie scattering theory and validated optical model. |
| pH of Aqueous Suspension | pH Meter | Determines pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per EP 2.2.3. |
Technical Specifications of Pyridine, 2-chloro-5-iodo-4-methyl-
| Test Item | Specification |
|---|---|
| Appearance | Colorless to off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Pyridine, 2-chloro-5-iodo-4-methyl-
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Pyridine, 2-chloro-5-iodo-4-methyl-
Safety Information of Pyridine, 2-chloro-5-iodo-4-methyl-
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Pyridine, 2-chloro-5-iodo-4-methyl-
Industrial Pyridine, 2-chloro-5-iodo-4-methyl- Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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