Andrographolide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 5508-58-7 |
| Product name | Andrographolide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Andrographolide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Andrographolide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Andrographolide
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Raw material for anti-inflammatory and antiviral drugs | Used in the synthesis of anti-inflammatory and antiviral drugs; serves as an intermediate in formulation manufacturing after extraction and purification |
| Pharmaceuticals | Treatment of respiratory tract infections | Formulated as injectables or tablets, with the compound as the primary active pharmaceutical ingredient (API) for treating common cold, pharyngitis, and bronchitis |
| Pharmaceuticals | Antipyretic and analgesic | Applied in adjunctive therapy for fever and inflammation-related conditions, leveraging its heat-clearing and detoxifying properties |
| Traditional Chinese Medicine (TCM) Preparations | Component of TCM formulations | Combined with other herbal ingredients in compound preparations such as Andrographis paniculata tablets and Andrographis paniculata dropping pills |
| Research | Natural product research subject | Used for structural modification and structure–activity relationship (SAR) studies to explore potential for novel drug development |
Manufacturing Quality Control of Andrographolide
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a reference standard using reversed-phase chromatography and UV detection at 225 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally similar impurities using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification via inductively coupled plasma mass spectrometry after acid digestion. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under controlled temperature and vacuum to determine volatile content. |
| Residue on Ignition | Sulfated Ash Gravimetry | Inorganic residue mass determined after high-temperature ignition following sulfuric acid treatment. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via iodine-sulfur dioxide reaction in pyridine-methanol medium. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size based on angular scattering pattern of laser beam passing through dispersed sample. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens using selective culture media. |
| pH of Solution | Potentiometric pH Measurement | Hydrogen ion activity measurement using calibrated glass electrode in aqueous suspension. |
Technical Specifications of Andrographolide
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 230–235 °C |
| Optical Rotation | -129.0 to -124.0 ° (c=1, in chloroform) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Andrographolide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Andrographolide
Packaging of Andrographolide
Industrial Andrographolide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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