China Factory Direct
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| CAS number | 5545-52-8 |
| Product name | N-Cbz-L-Aspartic acid 4-tert-butyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a protecting group in drug synthesis for preparing various bioactive compounds | Reacted with target molecules to form N-Cbz-protected intermediates, followed by deprotection under specific conditions to release the desired product |
| Organic Synthesis | Employed as a chiral auxiliary to construct chiral centers in asymmetric synthesis | Condensed with corresponding substrates to form chiral precursors containing the N-Cbz-L-aspartic acid structure; final chiral products are obtained via hydrolysis or other suitable methods |
| Biochemical Research | Applied in peptide and protein research and synthesis | Incorporated into peptide chains using solid-phase or solution-phase peptide synthesis techniques, leveraging its favorable solubility and stability to facilitate peptide assembly |
| Cosmetics | Formulated as a functional ingredient in skincare products | Chemically modified as required to enhance skin condition or serve as a moisturizing agent; typical processes include direct incorporation into formulations or microencapsulation |
| Food Additives | Rarely used, but potentially applicable in the food industry as a flavor enhancer or stabilizer | Subject to rigorous food safety evaluation to determine suitability; typically involves blending with food-grade materials and uniform dispersion throughout the product matrix via heating, mixing, or similar methods |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; individual impurities reported relative to main peak area. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., DCM, DMF, toluene) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 degrees C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantification of elemental impurities (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specific quantification of Pd residues (from coupling catalysts) after microwave-assisted digestion and ICP-MS analysis. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under controlled vacuum and temperature, reflecting volatile and moisture content. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in suspension using Mie scattering theory and laser diffraction instrumentation. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Optical Rotation | -12.0 to -10.0° (c=1, in DMF) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.