Methyldopa Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 555-30-6 |
| Product name | Methyldopa |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyldopa
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyldopa Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyldopa
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Treatment of hypertension as a centrally acting antihypertensive agent | Manufactured via chemical synthesis, primarily through dopamine receptor agonist mechanism |
| Chemical Research | Used as a chemical reagent for synthesizing other pharmaceuticals or studying pharmacological effects | Prepared via organic synthesis methods, commonly employed in pharmacological and biochemical research |
| Biotechnology | Studying neurotransmitter systems and associated physiological functions | Prepared via laboratory-scale synthesis and purification processes for biomedical research |
Manufacturing Quality Control of Methyldopa
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with that of the reference standard or standard spectrum to confirm its chemical structure characteristics. |
| High-Performance Liquid Chromatography (HPLC) | Qualitative identification based on retention time consistency with the reference standard. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase chromatographic column with a UV detector (typically around 280 nm) for quantification of the main component using external or internal standard methods. |
| Related Substances (Impurity) Test | High-Performance Liquid Chromatography (HPLC) | Use gradient or isocratic elution procedures to separate and detect organic impurities in methyldopa (such as degradation products, synthetic intermediates), and calculate impurity content by area normalization or self-reference method. |
| Moisture | Karl Fischer Method | Determine moisture content by quantitatively reacting water with iodine and sulfur dioxide in a pyridine/methanol system. |
| Dried Loss | Thermogravimetric Analysis (TGA) or Constant Pressure Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, and calculate the percentage of weight loss to evaluate total volatile substances and moisture. |
| Residue on Ignition | High-Temperature Ignition Method | Weigh the residual inorganic material after the sample is ignited at high temperature (approximately 700–800°C), used to control inorganic impurities. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or Thiocyanate Method | Determine specific heavy metals such as lead and cadmium using atomic absorption spectrometry, or use a colorimetric method (e.g., Chinese Pharmacopoeia General Rules) to control the limit of total heavy metals. |
| Residual Solvents | Gas Chromatography (GC) | Analyze via headspace or direct injection using an FID detector to detect organic solvents potentially remaining from synthesis (e.g., methanol, ethanol, acetone). |
| Optical Purity (Specific Rotation) | Specific Rotation Measurement Method | Determine the specific rotation of a methyldopa solution to verify its optical activity, which should conform to the specified requirements (methyldopa is a levorotatory compound). |
| pH Value | pH Meter Measurement Method | Measure the acidity or alkalinity of a prepared aqueous solution of a certain concentration using a calibrated pH meter to ensure compliance with pharmacopoeia requirements. |
Technical Specifications of Methyldopa
| Test Item | Specification |
|---|---|
| Appearance | Lightly pink solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 273-277°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -14.5 to -12.5° (c=1, H2O) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyldopa
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyldopa
Packaging of Methyldopa
Industrial Methyldopa Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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