2-FLUORO-5-HYDROXYPYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 55758-32-2 |
| Product name | 2-FLUORO-5-HYDROXYPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-FLUORO-5-HYDROXYPYRIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-FLUORO-5-HYDROXYPYRIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-FLUORO-5-HYDROXYPYRIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antiviral agents and kinase inhibitors | Produced via selective fluorination of 5-hydroxypyridine, followed by fluorination and hydroxylation steps, for constructing fluorinated heterocyclic drug scaffolds |
| Agrochemicals | Intermediate for synthesizing novel fluorinated fungicides and insecticides | Serves as a key structural unit in nucleophilic substitution or coupling reactions to introduce fluorine and hydroxyl functional groups, enhancing biological activity |
| Chemical Research | Organic building block for developing novel fluorinated heterocyclic compounds | Used to construct polysubstituted pyridine derivatives through functionalization reactions such as Suzuki coupling and Buchwald-Hartwig amination |
Manufacturing Quality Control of 2-FLUORO-5-HYDROXYPYRIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by retention time and peak area relative to the main peak. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures non-volatile inorganic residue after combustion with sulfuric acid treatment and high-temperature incineration. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid phase transition using calibrated capillary tube method. |
| Optical Rotation | Polarimetry | Measures specific rotation of chiral impurities or enantiomeric excess using sodium D-line light through a solution cell. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines acidity/basicity of a saturated aqueous suspension using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular variation in laser light scattering. |
| Organic Volatile Impurities (OVI) | GC-MS | Identifies and quantifies unspecified volatile organic impurities using gas chromatography coupled with mass spectrometry. |
Technical Specifications of 2-FLUORO-5-HYDROXYPYRIDINE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 48–52°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-FLUORO-5-HYDROXYPYRIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-FLUORO-5-HYDROXYPYRIDINE
Packaging of 2-FLUORO-5-HYDROXYPYRIDINE
Industrial 2-FLUORO-5-HYDROXYPYRIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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