Histamine dihydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 56-92-8 |
| Product name | Histamine dihydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Histamine dihydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Histamine dihydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Histamine dihydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmacological research tool to study histamine receptor function and mechanisms of allergic reactions | Applied in in vitro cell assays and animal models to induce allergic responses |
| Pharmaceuticals | Used for diagnosing gastric acid secretion function (histamine stimulation test) | Administered intravenously, followed by measurement of gastric fluid acidity and acid output |
| Chemical | Used as an organic synthesis intermediate for preparing histamine analogues or receptor agonists/antagonists | Employed as a starting material or functional group incorporation unit in multi-step organic synthesis |
| Biotechnology | Used in immunological research to model inflammatory responses and mast cell activation | Added quantitatively as histamine dihydrochloride to cell culture systems to trigger inflammatory signaling pathways |
| Education & Research | Used in teaching demonstrations of histamine’s physiological effects and receptor-mediated signal transduction | Applied in laboratory instruction to demonstrate histamine-induced smooth muscle contraction or increased vascular permeability |
Manufacturing Quality Control of Histamine dihydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies main component by titration with standardized NaOH solution using methyl red indicator. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying at 105 C for 2 hours to determine volatile content. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by ignition at 600 C and weighing residue. |
| Chloride Impurity | Argentometric Titration | Measures chloride ions via precipitation titration with silver nitrate using potassium chromate indicator. |
| Sulfate Impurity | Barium Sulfate Gravimetry | Precipitates sulfate as BaSO4 and determines mass after filtration and drying. |
| Heavy Metals | Colorimetric Limit Test (Lead Standard) | Compares sample color intensity with lead standard after reaction with thioacetamide under controlled pH. |
| Related Substances | HPLC-UV | Separates and quantifies impurities using reversed-phase HPLC with UV detection at 210 nm. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine-based reagent. |
| pH of Solution | Potentiometric Measurement | Measures hydrogen ion activity in 1% aqueous solution using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Quantifies chiral purity by measuring rotation of plane-polarized light at 20 C using sodium D line. |
| Melting Point | Capillary Melting Point Determination | Determines temperature range of solid-to-liquid transition using calibrated melting point apparatus. |
| Microbial Contamination | Membrane Filtration Assay | Detects viable aerobic microorganisms by filtration, membrane transfer, and incubation on soybean-casein digest agar. |
Technical Specifications of Histamine dihydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 215-219 °C (decomposes) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Histamine dihydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Histamine dihydrochloride
Packaging of Histamine dihydrochloride
Industrial Histamine dihydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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