2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 56177-80-1 |
| Product name | 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antitumor drug intermediate | Used in the synthesis of fluorouracil-based antitumor drugs via substitution reactions to introduce the 5-fluorouracil moiety, thereby enhancing inhibition of cancer cell proliferation |
| Pharmaceuticals | Antiviral research | Applied as a potential nucleoside analog in antiviral activity screening to evaluate inhibition against RNA or DNA viruses |
| Fine chemicals | Organic synthesis intermediate | Processed via catalyzed coupling or alkylation reactions in polar solvents to prepare novel pyrimidine derivatives for new drug development |
Manufacturing Quality Control of 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 265 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; individual impurities reported relative to main peak area. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual ethanol, dichloromethane, and other process solvents. |
| Water Content | Karl Fischer Titration | Volumetric titration with iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700 C followed by weighing of non-volatile residue to assess inorganic impurities. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and absence of racemization. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to report D10, D50, and D90 values. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH measurement of 1% w/v suspension in purified water using calibrated pH electrode. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens per pharmacopeial methods. |
Technical Specifications of 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 218-222°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
Safety Information of 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
Industrial 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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