China Factory Direct
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| CAS number | 56502-01-3 |
| Product name | Boc-L-beta-Homoproline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical intermediates | Used as a chiral auxiliary in the synthesis of β-lactam antibiotics |
| Pharmaceutical R&D | Peptide synthesis | Applied as protected amino acid derivatives for peptide chain elongation |
| Pharmaceutical R&D | Chiral catalysts | Employed as chiral ligands or structural units in asymmetric catalysis |
| Biochemistry | Enzyme substrate analogs | Used to synthesize inhibitors or probe molecules for specific enzymes |
| Chemical synthesis | Conformationally constrained amino acids | Applied as amino acid analogs with conformational constraints in protein structure–function studies |
| Organic synthesis | Organic reaction reagents | Used to construct chiral centers in complex molecule synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination using a chiral stationary phase with UV detection, resolving L- and D-diastereomers. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in pyridine-methanol buffer. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., DMF, THF, ethyl acetate) using capillary GC with flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, based on mass-to-charge ratio detection. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue via plasma excitation and optical emission at characteristic wavelengths. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a polarimeter at 20 deg C with sodium D-line (589 nm) light. |
| Related Substances | HPLC-UV | Detection and quantification of structurally similar impurities (e.g., Boc-deprotected product, diastereomers) using gradient reversed-phase HPLC. |
| pH (1% w/v aqueous solution) | Potentiometric Titration | Measurement of hydrogen ion activity using calibrated glass electrode in aqueous suspension. |
| Loss on Drying | Gravimetric Analysis | Mass loss determination after drying under controlled temperature and vacuum to remove volatile components. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to calculate volume-based particle size distribution in dispersed solid sample. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms by filtration, membrane transfer to agar media, and colony counting after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 168-172°C |
| Optical Rotation | -30.5 to -28.5° (c=1, in DMF) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.