D-Phenylglycinol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 56613-80-0 |
| Product name | D-Phenylglycinol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-Phenylglycinol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-Phenylglycinol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-Phenylglycinol
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral Drug Intermediates | Serves as a chiral building block in the synthesis of β-lactam antibiotics (e.g., certain penicillin derivatives) and other chiral active pharmaceutical ingredients |
| Pharmaceutical Industry | Chiral Ligand Synthesis | Used to prepare chiral oxazoline ligands for asymmetric catalysis (e.g., asymmetric addition, coupling reactions) |
| Pharmaceutical Industry | Enzyme Inhibitor Synthesis | Applied in the synthesis of specific enzyme inhibitor drugs |
Manufacturing Quality Control of D-Phenylglycinol
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase C18 column with UV detection (typically at 210–230 nm), employing water-organic solvent (e.g., methanol or acetonitrile) as the mobile phase. Quantification of D-phenylglycinol is performed using external standard or internal standard methods. Offers excellent separation efficiency and high sensitivity. |
| Purity Analysis | Gas Chromatography (GC) | Applicable to volatile samples; after derivatization, samples are injected into a capillary column for separation and detected by Flame Ionization Detector (FID). Used to quantify impurity peaks and assess main component purity. Suitable for residual solvents and organic impurities analysis. |
| Enantiomeric Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Employs chiral stationary phase columns (e.g., Chiralpak AD-H, AS-H), enabling separation of D- and L-phenylglycinol enantiomers. Used to determine enantiomeric excess (ee value) and ensure optical purity. |
| Residual Solvents | Gas Chromatography (GC) | Follows pharmacopeial methods (e.g., Chinese Pharmacopoeia, USP). Uses headspace GC to detect organic solvents (e.g., methanol, ethanol, acetone) remaining from production processes, ensuring compliance with specified limits. |
| Moisture Content | Karl Fischer Titration | Based on the reaction between iodine and sulfur dioxide in an anhydrous environment with water. Utilizes potentiometric titration to accurately measure trace moisture levels in samples. Ideal for low-level moisture determination. |
| Melting Point Determination | Melting Point Apparatus Method | Determines the melting temperature range of D-phenylglycinol using automated or manual melting point instruments, assessing crystalline purity and material consistency. Pure substances exhibit a defined melting point range. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, quantifies heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmaceutical or industrial standards. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Builds upon content determination methods by optimizing gradient elution programs to detect potential synthetic intermediates and degradation products. Typically reports individual and total impurity levels. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Uses ¹H-NMR and ¹³C-NMR spectra to confirm molecular structure and stereochemistry, commonly applied for identification of starting materials or key intermediates. |
| Infrared Spectroscopy | Fourier Transform Infrared Spectroscopy (FT-IR) | Measures infrared absorption spectra by pressing samples into pellets or using ATR method. Compares characteristic functional group peaks (e.g., hydroxyl, amino groups) with reference spectra for identification purposes. |
Technical Specifications of D-Phenylglycinol
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 68~72°C |
| Optical Rotation | -31.0 ~ -28.0° (c=1, in methanol) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-Phenylglycinol
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NMR Spectra of D-Phenylglycinol
Packaging of D-Phenylglycinol
Industrial D-Phenylglycinol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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